Aggravating mechanisms from COVID-19

JH Lee, C Sergi, RE Kast, BA Kanwar, J Bourbeau… - Virology Journal, 2024 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated
diseases. The pathophysiology of COVID-19 uses the following three mechanisms:(1) …

Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer's Disease

N Navolokin, V Adushkina, D Zlatogorskaya… - Pharmaceuticals, 2024 - mdpi.com
The COVID-19 pandemic, caused by infection with the SARS-CoV-2 virus, is associated with
cognitive impairment and Alzheimer's disease (AD) progression. Once it enters the brain, the …

[HTML][HTML] Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells–Implications for Alzheimer's disease

L Mussalo, R Lampinen, S Avesani, T Závodná… - Redox biology, 2024 - Elsevier
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of≤ 0.1 μm, are
considerably related to traffic emissions. Several studies link air pollution to Alzheimer's …

[HTML][HTML] Exposure to urban particulate matter alters responses of olfactory mucosal cells to SARS-CoV-2 infection

MA Shahbaz, S Kuivanen, L Mussalo, AM Afonin… - Environmental …, 2024 - Elsevier
Respiratory viruses have a significant impact on health, as highlighted by the COVID-19
pandemic. Exposure to air pollution can contribute to viral susceptibility and be associated …

Nasal Mucociliary Epithelial Cell Culture Models for Studying Viral Infections

G Balistreri - Influenza Virus: Methods and Protocols, 2025 - Springer
Respiratory nasal or lung epithelial cells serve as a valuable in vitro model for studying
respiratory viral infections due to their physiological relevance and ability to recapitulate key …

A Protocol for Neuralized Murine Olfactory Organoids

A Ozgun, P Suman, J Coulombe… - bioRxiv, 2024 - biorxiv.org
Chronic olfactory dysfunction can be associated with parkinsonism, dementia, demyelinating
disorders and schizophrenia. The olfactory epithelium (OE) represents an interface between …

The picture theory of seven pathways associated with COVID-19 in the real world

J hoon Lee, C Sergi, RE Kast, BA Kanwar… - 2024 - researchsquare.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated
diseases. Interactions between the host and virus govern induction, resulting in multiorgan …

Innovative approaches in the characterization of xenobiotic metabolizing enzymes of the nasal tissues: from the animal to human tissue engineering

J Mérignac-Lacombe - 2024 - theses.hal.science
Our sensitive olfaction relies on Xenobiotic Metabolizing Enzymes (XMEs) that protect the
nasal tissue from potentially harmful volatile compounds, but also quickly terminate the …