CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and
progenitor cells. Clinically, it is associated with the selection and enrichment of …

It has always been an ambitious goal in medicine to repair or replace morbid tissues for
regaining the organ functionality. This challenge has recently gained momentum through …

Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …

The cornea is a tough transparent tissue admitting and focusing light in the eye. More than
90% of the cornea is stroma, a highly organized, transparent connective tissue maintained …

Introduction• Mesenchymal stem cells and its characteristics• Experimental/preclinical MSC‐
based studies–MSC transplantation–Genetically modified MSC‐based therapy–MSC‐based …

The cornea is our window to the world and our vision is critically dependent on corneal
clarity and integrity. Its epithelium represents one of the most rapidly regenerating …

Stem cells (SC) are able to self-renew and to differentiate into many types of committed cells,
making SCs interesting for cellular therapy. However, the pool of SCs in vivo and in vitro …

Stem cell-based therapy has become an attractive and promising approach for the treatment
of severe injuries or thus-far incurable diseases. However, the use of stem cells is often …

Pancreatic stellate cell (PSC) is a type of pluripotent cell located between pancreatic lobules
and the surrounding area of acinars. When activated, PSC can be transformed into …

The increase of pro-inflammatory cytokines and oxidative stress leads to β-cell damage and
promotes β-cells apoptosis, in types I and II of diabetes mellitus. Therefore, blocking of pro …