Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Inherited platelet disorders are important conditions that often manifest with bleeding. These
disorders have heterogeneous underlying pathologies. Some are syndromic disorders with …

Background Ultra-rare inherited bleeding disorders (BDs) present important challenges for
generating a strong evidence foundation for optimal diagnosis and management. Without …

Deleterious germ line RUNX1 variants cause the autosomal dominant familial platelet
disorder with associated myeloid malignancy (FPDMM), characterized by thrombocytopenia …

Background The future bleeding risk, especially after hemostatic challenges, and thus the
requirement for hemostatic treatment in patients with mild-to-moderate bleeding disorders …

Abstract Background Inherited platelet disorders (IPDs) are rare diseases characterized by
reduced blood platelet counts and/or impaired platelet function. Recognizing IPDs is …

Platelets are major regulators of haemostasis and coagulation. The primary role of platelets
in coagulation is to form a stable clot and stop bleeding. Studies of platelet phenotype and …

A bleeding tendency is one of the most common complaints observed by hematologists. It is
challenging to differentiate a clinically insignificant bleeding from a bleeding phenotype that …

Introduction Platelet function tests are used to screen and diagnose patients with possible
inherited platelet function defects (IPFD). Some acquired platelet dysfunction may be caused …

ABSTRACT Introduction Inherited bleeding disorders (IBDs) including hemophilia, von
Willebrand disease, platelet disorders, mucocutaneous bleeding disorders and coagulation …