The recapitulation of complex microenvironments that regulate cell behavior during
development, disease, and wound healing is key to understanding fundamental biological …

Marine polysaccharides (MPs) are exceptional bioactive materials that possess unique
biochemical mechanisms and pharmacological stability, making them ideal for various …

Background Cartilage injury and pathological degeneration are reported in millions of
patients globally. Cartilages such as articular hyaline cartilage are characterized by poor self …

Articular cartilage is a highly specialised connective tissue of diarthrodial joints which
provides a smooth, lubricated surface for joint articulation and plays a crucial role in the …

Cartilage injury is difficult to self-repair, which poses a challenge to scaffold design and
selection of seeded cells for cartilage tissue engineering. In this study, we presented a …

Successful recapitulation of the anatomical microarchitecture and biomechanics of the
native articular cartilage under in vitro culture conditions is still an elusive topic of research …

The role of regenerative medicine in clinical therapies is becoming increasingly vital. Under
specific conditions, mesenchymal stem cells (MSCs) are capable of differentiating into …

Functional ability is the basis of healthy aging. Articular cartilage degeneration is amongst
the most prevalent degenerative conditions that cause adverse impacts on the quality of life; …

Bioengineered materials represent an innovative option to support the regenerative
processes of damaged tissues, with the final objective of creating a functional environment …

In this study, we developed a composite hydrogel based on Gellan gum containing
Boswellia serrata extract (BSE). BSE was either incorporated directly or loaded into an MgAl …