Facing up to the global challenges of ageing

L Partridge, J Deelen, PE Slagboom - Nature, 2018‏ - nature.com
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

The prevalence and risk factors of hypertension among the urban population in Southeast Asian countries: a systematic review and meta‐analysis

A Mohammed Nawi, Z Mohammad… - International journal …, 2021‏ - Wiley Online Library
The trend of global prevalence for hypertension has been dramatically increasing for the
past two decades in Southeast Asian countries. A systematic review aiming to assess the …

Association of systolic blood pressure with dementia risk and the role of age, U-shaped associations, and mortality

JW van Dalen, C Brayne, PK Crane… - JAMA internal …, 2022‏ - jamanetwork.com
Importance The optimal systolic blood pressure (SBP) to minimize the risk of dementia in
older age is unknown. Objective To investigate whether the association between SBP and …

Factors influencing transitions between frailty states in elderly adults: The Progetto Veneto Anziani Longitudinal Study

C Trevisan, N Veronese, S Maggi… - Journal of the …, 2017‏ - Wiley Online Library
Objectives To investigate frailty state transitions in a cohort of older Italian adults to identify
factors exacerbating or improving frailty conditions. Design Population‐based longitudinal …

Definition, criteria, and core concepts of guidelines for the management of obesity disease in Japan

W Ogawa, Y Hirota, S Miyazaki, T Nakamura… - Endocrine …, 2024‏ - jstage.jst.go.jp
To identify those who might benefit from weight reduction within a large population of obese
individuals, Japan Society for the Study of Obesity (JASSO) advocated the concept of …

Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning

S Lee, J Zhou, WT Wong, T Liu, WKK Wu… - BMC endocrine …, 2021‏ - Springer
Introduction Recent studies have reported that HbA1c and lipid variability is useful for risk
stratification in diabetes mellitus. The present study evaluated the predictive value of the …

[HTML][HTML] The obesity paradox in kidney disease: how to reconcile it with obesity management

K Kalantar-Zadeh, CM Rhee, J Chou… - Kidney international …, 2017‏ - Elsevier
Obesity, a risk factor for de novo chronic kidney disease (CKD), confers survival advantages
in advanced CKD. This so-called obesity paradox is the archetype of the reverse …

[HTML][HTML] Association of conventional cardiovascular risk factors with cardiovascular disease after hypertensive disorders of pregnancy: analysis of the Nord-Trøndelag …

EB Haug, J Horn, AR Markovitz, A Fraser… - JAMA …, 2019‏ - jamanetwork.com
Importance Women with a history of hypertensive disorders of pregnancy (HDP) have higher
risk of cardiovascular disease (CVD). It is not known how much of the excess CVD risk in …

Multimorbidity patterns and their relationship to mortality in the US older adult population

DD Zheng, DA Loewenstein, SL Christ, DJ Feaster… - PLoS …, 2021‏ - journals.plos.org
Background Understanding patterns of multimorbidity in the US older adult population and
their relationship with mortality is important for reducing healthcare utilization and improving …

Metabolic endotoxemia and cardiovascular disease: A systematic review about potential roles of prebiotics and probiotics

J Moludi, V Maleki, H Jafari‐Vayghyan… - Clinical and …, 2020‏ - Wiley Online Library
Translocation of microbiome‐derived lipopolysaccharide (LPS) to the bloodstream
(metabolic endotoxaemia) is associated with a significantly increased risk of cardiovascular …