Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …

Biomolecular condensation processes are increasingly recognized as a fundamental
mechanism that living cells use to organize biomolecules in time and space. These …

Antimicrobial peptides (AMPs), which combat bacterial infections by disrupting the bacterial
cell membrane or interacting with intracellular targets, are naturally produced by a number of …

HMGA1 is an abundant non-histone chromatin protein that has been implicated in
embryonic development, cancer, and cellular senescence, but its specific role remains …

Abstract The SARS-CoV-2 Nucleocapsid (N) protein is responsible for condensation of the
viral genome. Characterizing the mechanisms controlling nucleic acid binding is a key step …

Cellular senescence, a persistent form of cell cycle arrest, has been linked to the formation
of heterochromatic foci, accompanied by additional concentric epigenetic layers. However …

Identification of factors that regulate chromatin condensation is important for understanding
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …

Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

Cellular senescence is implicated in a wide range of physiological and pathological
conditions throughout an organism's entire lifetime. In particular, it has become evident that …

The three-dimensional organisation of the genome modulates biological processes and is,
in turn, transformed by the activity in the nucleus. Not surprisingly, understanding how the …