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Role of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent model
RW Olsen, J Liang - Molecular brain, 2017 - Springer
GABAergic inhibitory transmission is involved in the acute and chronic effects of ethanol on
the brain and behavior. One-dose ethanol exposure induces transient plastic changes in …
the brain and behavior. One-dose ethanol exposure induces transient plastic changes in …
Looking for Novelty in an “Old” Receptor: Recent Advances Toward Our Understanding of GABAARs and Their Implications in Receptor Pharmacology
Diverse populations of GABAA receptors (GABAARs) throughout the brain mediate fast
inhibitory transmission and are modulated by various endogenous ligands and therapeutic …
inhibitory transmission and are modulated by various endogenous ligands and therapeutic …
GABAA receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol
D Chandra, F Jia, J Liang, Z Peng… - Proceedings of the …, 2006 - pnas.org
The neurotransmitter GABA mediates the majority of rapid inhibition in the CNS. Inhibition
can occur via the conventional mechanism, the transient activation of subsynaptic GABAA …
can occur via the conventional mechanism, the transient activation of subsynaptic GABAA …
Withdrawal from 3α-OH-5α-pregnan-20-one using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the …
In the present study, we have characterized properties of steroid withdrawal using a
pseudopregnant rat model. This paradigm results in increased production of endogenous …
pseudopregnant rat model. This paradigm results in increased production of endogenous …
Single-channel properties of synaptic and extrasynaptic GABAA receptors suggest differential targeting of receptor subtypes
Many neurons express a multiplicity of GABAA receptor subunit isoforms. Despite having
only a single source of inhibitory input, the cerebellar granule cell displays, at various stages …
only a single source of inhibitory input, the cerebellar granule cell displays, at various stages …
Region-specific developmental specialization of GABA–glycine cosynapses in laminas I–II of the rat spinal dorsal horn
AF Keller, JAM Coull, N Chery, P Poisbeau… - Journal of …, 2001 - jneurosci.org
The spinal dorsal horn is the first level of the CNS in which nociceptive input from sensory
afferents is integrated and transmitted. Although inhibitory control in this region has a crucial …
afferents is integrated and transmitted. Although inhibitory control in this region has a crucial …
Modulation of synaptic GABAA receptor function by PKA and PKC in adult hippocampal neurons
P Poisbeau, MC Cheney, MD Browning… - Journal of …, 1999 - jneurosci.org
Several protein kinases are known to phosphorylate Ser/Thr residues of certain GABAA
receptor subunits. Yet, the effect of phosphorylation on GABAA receptor function in neurons …
receptor subunits. Yet, the effect of phosphorylation on GABAA receptor function in neurons …
Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses
D Perrais, N Ropert - Journal of Neuroscience, 1999 - jneurosci.org
GABAA-mediated miniature IPSCs (mIPSCs) were recorded from layer V pyramidal neurons
of the visual cortex using whole-cell patch-clamp recording in rat brain slices. At room …
of the visual cortex using whole-cell patch-clamp recording in rat brain slices. At room …
Cell surface stability of γ-aminobutyric acid type A receptors: Dependence on protein kinase C activity and subunit composition
CN Connolly, JT Kittler, P Thomas, JM Uren… - Journal of Biological …, 1999 - jbc.org
Type A γ-aminobutyric acid receptors (GABA A), the major sites of fast synaptic inhibition in
the brain, are believed to be composed predominantly of α, β, and γ subunits. Although cell …
the brain, are believed to be composed predominantly of α, β, and γ subunits. Although cell …
[BUCH][B] Diversity in the neuronal machine: order and variability in interneuronal microcircuits
I Soltesz - 2006 - books.google.com
This book is a colorful journey into the fascinatingly diverse world of interneurons, an
important class of highly heterogeneous cells found in all cortical neuronal networks …
important class of highly heterogeneous cells found in all cortical neuronal networks …