Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work
conducted over the last decades has defined the major mRNA decay pathways, as well as …

Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to
intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying …

The RIG-I like receptors (RLRs) RIG-I and MDA5 are cytosolic RNA helicases best
characterized as restriction factors for RNA viruses. However, evidence suggests RLRs …

Research on non‐coding RNA (nc RNA) is a rapidly expanding field. Providing an official
gene symbol and name to nc RNA genes brings order to otherwise potential chaos as it …

Chemical modifications of RNA molecules regulate both RNA metabolism and fate. The
deposition and function of these modifications are mediated by the actions of writer, reader …

Vault RNAs (vtRNA) are small non-coding RNAs transcribed by RNA polymerase III found in
many eukaryotes. Although they have been linked to drug resistance, apoptosis, and viral …

High-throughput sequencing of miRNAs has revealed the diversity and variability of mature
and functional short noncoding RNAs, including their genomic origins, biogenesis pathways …

Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short,
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …

Cells secrete extracellular RNA (exRNA) to their surrounding environment and exRNA has
been found in many body fluids such as blood, breast milk and cerebrospinal fluid. However …