Celiac disease: understanding the gluten-free diet
KA Bascuñán, MC Vespa, M Araya - European journal of nutrition, 2017 - Springer
Purpose The only effective and safe treatment of celiac disease (CD) continues being strict
exclusion of gluten for life, the so-called gluten-free diet (GFD). Although this treatment is …
exclusion of gluten for life, the so-called gluten-free diet (GFD). Although this treatment is …
The role of diet and gut microbiota in regulating gastrointestinal and inflammatory disease
Diet is an important lifestyle factor that is known to contribute in the development of human
disease. It is well established that poor diet plays an active role in exacerbating metabolic …
disease. It is well established that poor diet plays an active role in exacerbating metabolic …
IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction
In this Opinion article, we discuss the function of tissues as a crucial checkpoint for the
regulation of effector T cell responses, and the notion that interleukin-15 (IL-15) functions as …
regulation of effector T cell responses, and the notion that interleukin-15 (IL-15) functions as …
T cells in celiac disease
Celiac disease is a human T cell–mediated autoimmune-like disorder caused by exposure
to dietary gluten in genetically predisposed individuals. This review will discuss how CD4 T …
to dietary gluten in genetically predisposed individuals. This review will discuss how CD4 T …
Celiac disease: from pathogenesis to novel therapies
Celiac disease has become one of the best-understood HLA-linked disorders. Although it
shares many immunologic features with inflammatory bowel disease, celiac disease is …
shares many immunologic features with inflammatory bowel disease, celiac disease is …
To respond or not to respond—a personal perspective of intestinal tolerance
AMI Mowat - Nature Reviews Immunology, 2018 - nature.com
For many years, the intestine was one of the poor relations of the immunology world, being a
realm inhabited mostly by specialists and those interested in unusual phenomena. However …
realm inhabited mostly by specialists and those interested in unusual phenomena. However …
Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease
Background The adaptive immune system is central to the development of coeliac disease.
Adaptive immune responses are, however, controlled by a preceding activation of the innate …
Adaptive immune responses are, however, controlled by a preceding activation of the innate …
A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease
S Hüe, JJ Mention, RC Monteiro, SL Zhang, C Cellier… - Immunity, 2004 - cell.com
MICA molecules interact with the NKG2D-activating receptor on human NK and CD8 T cells.
We investigated the participation of the MICA/NKG2D pathway in the destruction of intestinal …
We investigated the participation of the MICA/NKG2D pathway in the destruction of intestinal …
IL‐15: a central regulator of celiac disease immunopathology
Summary Interleukin‐15 (IL‐15) exerts many biological functions essential for the
maintenance and function of multiple cell types. Although its expression is tightly regulated …
maintenance and function of multiple cell types. Although its expression is tightly regulated …
[HTML][HTML] Celiac disease: role of the epithelial barrier
M Schumann, B Siegmund, JD Schulzke… - Cellular and molecular …, 2017 - Elsevier
In celiac disease (CD) a T-cell–mediated response to gluten is mounted in genetically
predisposed individuals, resulting in a malabsorptive enteropathy histologically highlighted …
predisposed individuals, resulting in a malabsorptive enteropathy histologically highlighted …