Extended-spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options

G Peirano, JDD Pitout - Drugs, 2019 - Springer
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are a major global
public health concern. Presently, Escherichia coli with CTX-Ms are the most common …

[HTML][HTML] Burden of bacterial bloodstream infection—a brief update on epidemiology and significance of multidrug-resistant pathogens

WV Kern, S Rieg - Clinical Microbiology and Infection, 2020 - Elsevier
Background Bloodstream infections comprise a wide variety of pathogens and clinical
syndromes with considerable overlap with similar syndromes of non-bacteraemic infections …

Klebsiella pneumoniae bacteremia mortality: a systematic review and meta-analysis

D Li, X Huang, H Rao, H Yu, S Long, Y Li… - Frontiers in Cellular and …, 2023 - frontiersin.org
Objective To analyze the mortality rate of patients with Klebsiella pneumoniae bacteremia
(KPB) and the impact of extended spectrum beta-lactamase (ESBL) producing or …

Treatment of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLs) infections: what have we learned until now?

ZD Pana, T Zaoutis - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
The spread of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae
(ESBL-PE) has dramatically increased worldwide, and this “evolving crisis” is currently …

[HTML][HTML] Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages

A Fostervold, N Raffelsberger, MAK Hetland… - Journal of Infection, 2024 - Elsevier
Background Klebsiella pneumoniae species complex (KpSC) bloodstream infections (BSIs)
are associated with considerable morbidity and mortality, particularly in elderly and …

Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods

K Lindstedt, D Buczek, T Pedersen, E Hjerde… - Gut …, 2022 - Taylor & Francis
Klebsiella pneumoniae is an important opportunistic healthcare-associated pathogen and
major contributor to the global spread of antimicrobial resistance. Gastrointestinal …

Clonal background and routes of plasmid transmission underlie antimicrobial resistance features of bloodstream Klebsiella pneumoniae

OO Ikhimiukor, NI Zac Soligno, IJ Akintayo… - Nature …, 2024 - nature.com
Bloodstream infections caused by the opportunistic pathogen Klebsiella pneumoniae are
associated with adverse health complications and high mortality rates. Antimicrobial …

Carbapenem-sparing strategy: carbapenemase, treatment, and stewardship

S Corcione, T Lupia, AE Maraolo… - Current Opinion in …, 2019 - journals.lww.com
Summary stewardship programs may be useful in reducing probable misuse and overuse of
antibiotics, which has probably contributed to the emergence of carbapenem-resistant …

[HTML][HTML] Infections caused by extended-spectrum β-lactamase-producing Enterobacterales after rectal colonization with ESBL-producing Escherichia coli or Klebsiella …

LA Denkel, F Maechler, F Schwab, A Kola… - Clinical Microbiology …, 2020 - Elsevier
Objectives Infections as a result of extended-spectrum β-lactamase-producing
Enterobacterales (ESBL-E) are considered infections with a high public health burden. In …

Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage …

N Raffelsberger, DJ Buczek, K Svendsen… - Msphere, 2023 - journals.asm.org
The global prevalence of infections caused by extended-spectrum β-lactamase-producing
Enterobacterales (ESBL-E) is increasing, and for Escherichia coli, observations indicate that …