Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery
G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …
restricted by low drug loading, complex preparation technology, and potential toxicity …
Lipid–drug conjugate for enhancing drug delivery
D Irby, C Du, F Li - Molecular pharmaceutics, 2017 - ACS Publications
Lipid–drug conjugates (LDCs) are drug molecules that have been covalently modified with
lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes …
lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes …
Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents
The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …
Nanotechnology in colorectal cancer for precision diagnosis and therapy
Colorectal cancer (CRC) is the third most frequently occurring tumor in the human
population. CRCs are usually adenocarcinomatous and originate as a polyp on the inner …
population. CRCs are usually adenocarcinomatous and originate as a polyp on the inner …
Mesoporous silica nanoparticle based enzyme responsive system for colon specific drug delivery through guar gum cap**
B Kumar, S Kulanthaivel, A Mondal, S Mishra… - Colloids and Surfaces B …, 2017 - Elsevier
In the global context of increasing colonic diseases, colon specific oral drug delivery
systems have shown promise as an effective therapeutic modality. Herein, we developed a …
systems have shown promise as an effective therapeutic modality. Herein, we developed a …
Engineered nanoparticles for imaging and drug delivery in colorectal cancer
Colorectal cancer (CRC) is one of the deadliest diseases worldwide due to a lack of early
detection methods and appropriate drug delivery strategies. Conventional imaging …
detection methods and appropriate drug delivery strategies. Conventional imaging …
Integrating cutting-edge technologies: AI, IoT, blockchain and nanotechnology for enhanced diagnosis and treatment of colorectal cancer-A review
P Pandurangan, AD Rakshi, MSA Sundar… - Journal of Drug Delivery …, 2024 - Elsevier
Currently adopted methods that are used for diagnosis and treatment are not effective in the
successful management of CRC. Nanotechnology has explored a new beginning to the …
successful management of CRC. Nanotechnology has explored a new beginning to the …
Penetrable nanoplatform for “cold” tumor immune microenvironment reeducation
Q Chen, Y He, Y Wang, C Li, Y Zhang, Q Guo… - Advanced …, 2020 - Wiley Online Library
Lack of tumor‐infiltration lymphocytes (TILs) and resistances by overexpressed
immunosuppressive cells (principally, myeloid‐derived suppressor cells (MDSCs)) in tumor …
immunosuppressive cells (principally, myeloid‐derived suppressor cells (MDSCs)) in tumor …
Self-assembled lipid–prodrug nanoparticles
Nanomedicines suffer from poor drug loading and uncontrolled 'burst release'after
administration. Combining prodrug strategies with nanostructured carriers can help to …
administration. Combining prodrug strategies with nanostructured carriers can help to …
Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery
Once introduced in the organism, the interaction of nanoparticles with various biomolecules
strongly impacts their fate. Here we show that nanoparticles made of the squalene derivative …
strongly impacts their fate. Here we show that nanoparticles made of the squalene derivative …