Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …

Low back pain is a major public health concern experienced by 80% of the world's
population during their lifetime, which is closely associated with intervertebral disc (IVD) …

Bone defect is usually difficult to recover quickly, and bone scaffold transplantation is
considered to be an effective method. Biomaterials have a wide range of application …

Tissue-engineered approaches for the treatment of early-stage intervertebral disc
degeneration have shown promise in preclinical studies. However, none of these therapies …

Intervertebral disc (IVD) degeneration is a common cause of low back pain and most spinal
disorders. As IVD degeneration is a major obstacle to the healthy life of so many individuals …

Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

From degeneration causing intervertebral disc issues to trauma‐induced meniscus tears,
diverse factors can injure the different types of cartilage. This review highlights adhesives as …

Annulus fibrosus (AF) impairment is associated with reherniation, discogenic pain, and disc
degeneration after surgical partial discectomy. Due to a limited intrinsic healing capacity …

Low back pain is one of the most serious public health problems worldwide and the major
clinical manifestation of intervertebral disc degeneration (IVDD). The key pathological …

Low back pain is the major cause of disability worldwide, and intervertebral disc
degeneration (IVDD) is one of the most important causes of low back pain. Currently, there is …