Ulcerative colitis (UC) and Crohn's disease (CD) are the major forms of inflammatory bowel
diseases (IBD) in man. Despite some common features, these forms can be distinguished by …

Background: Accumulated evidence indicates that astragalus polysaccharide (APS) may
have a beneficial impact on ulcerative colitis (UC) by suppressing inflammation and …

Objective: Few real-world studies have shown clear association between interleukin (IL)-17
inhibitors and inflammatory bowel disease (IBD) onset. This study investigated the reporting …

Background & Aims Polygenic and environmental factors are underlying causes of
inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci …

Objectives Previous studies have confirmed a link between specific inflammatory cytokines
and inflammatory bowel disease (IBD), but the causal relationship between them is not …

Ruminococcus gnavus (R. gnavus) is a gram-positive anaerobe commonly resides in the
human gut microbiota. The advent of metagenomics has linked R. gnavus with various …

Cannabinoids are emerging as promising treatments for inflammatory diseases such as
ulcerative colitis. Specifically, cannabinoid 2 (CB2) receptors, which are upregulated during …

AIM To investigate the role of the miR-133a-UCP2 pathway in the pathogenesis of
inflammatory bowel disease (IBD) and to explore the potential downstream mechanisms …

Immune-mediated diseases (IMDs) arise when tolerance is lost and chronic inflammation is
targeted towards healthy tissues. Despite their growing prevalence, therapies to treat IMDs …

NSAIDs (Non-steroidal anti-inflammatory drugs) show its effect by preventing prostaglandin
synthesis, which reasons ulcer complications and mucosal damage all over the …