Multifaceted evaluation of pyrazole derivative (T4)-chitosan (CS) nanoparticles: Morphology, drug release, and anti-tumor efficacy in a rat model

R Murugan, SPRR Nayak, B Haridevamuthu… - International Journal of …, 2024 - Elsevier
The development of targeted nanotherapeutics has emerged as a pivotal advancement in
cancer treatment, aiming to enhance the efficacy and specificity of drug delivery while …

Advancements in the Synthesis and Functionalization of Zinc Oxide-Based Nanomaterials for Enhanced Oral Cancer Therapy

J Pei, PM Natarajan, VR Umapathy, B Swamikannu… - Molecules, 2024 - mdpi.com
The fabrication of zinc oxide-based nanomaterials (including natural and synthetic polymers
like sulfated polysaccharide, chitosan, and polymethyl methacrylate) has potential to …

[HTML][HTML] Cytotoxicity and targeted drug delivery of green synthesized metallic nanoparticles against oral Cancer: A review

M Maghimaa, S Sagadevan, PR Suryadevara… - Inorganic Chemistry …, 2025 - Elsevier
Recent advancements in nanotechnology have significantly contributed to develo**
innovative approaches in cancer therapy, particularly for oral cancer. This review focuses on …

Multifunctional curcumin mediated zinc oxide nanoparticle enhancing biofilm inhibition and targeting apoptotic specific pathway in oral squamous carcinoma cells

JZ Tayyeb, M Priya, A Guru, MS Kishore Kumar… - Molecular Biology …, 2024 - Springer
Background Oral health remains a significant global concern with the prevalence of oral
pathogens and the increasing incidence of oral cancer posing formidable challenges …

Zinc oxide nanoparticles functionalized with cinnamic acid for targeting dental pathogens receptor and modulating apoptotic genes in human oral epidermal …

OV Ravikumar, V Marunganathan, MSK Kumar… - Molecular Biology …, 2024 - Springer
Background Oral diseases are often attributed to dental pathogens such as S. aureus, S.
mutans, E. faecalis, and C. albicans. In this research work, a novel approach was employed …

Exploring the anticancer and antioxidant potential of gold nanoparticles synthesized from Pterocarpus marsupium bark extract against oral squamous cell carcinoma

S Samal, RK Meher, PK Das, SK Swain… - Artificial Cells …, 2024 - Taylor & Francis
Oral squamous cell carcinoma (OSCC) is a disease of significant concern with higher
mortality rates. Conventional treatment approaches have several drawbacks, leading to the …

Enhancing the efficacy of zinc oxide nanoparticles by beta-carotene conjugation for improved anti-microbial and anti-tumor therapy for dental application

MR Shaik, SP Panda, SA Hussain… - Pharmaceutical …, 2025 - Taylor & Francis
Abstract Zinc oxide NPs (ZnO NPs) are notable in nanomedicine for their exceptional
physicochemical and biological properties. This study synthesizes and characterizes beta …

Synergistic Action of Rutin‐Coated Zinc Oxide Nanoparticles: Targeting Biofilm Formation Receptors of Dental Pathogens and Modulating Apoptosis Genes for …

MR Shaik, M Ramasamy, D Jain… - … of Biochemical and …, 2024 - Wiley Online Library
Oral diseases are often associated with bacterial and fungal pathogens such as
Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, and Candida …

Avellanin A Has an Antiproliferative Effect on TP-Induced RWPE-1 Cells via the PI3K-Akt Signalling Pathway

C Xu, G Cao, H Zhang, M Bai, X Yi, X Qu - Marine Drugs, 2024 - mdpi.com
Cyclic pentapeptide compounds have garnered much attention as a drug discovery
resource. This study focused on the characterization and anti-benign prostatic hyperplasia …

Piperine-coated zinc oxide nanoparticles target biofilms and induce oral cancer apoptosis via BCl-2/BAX/P53 pathway

MR Shaik, K Kandaswamy, A Guru, H Khan, J Giri… - BMC Oral Health, 2024 - Springer
Background Dental pathogens play a crucial role in oral health issues, including tooth
decay, gum disease, and oral infections, and recent research suggests a link between these …