GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives

R Nevola, R Epifani, S Imbriani, G Tortorella… - International Journal of …, 2023 - mdpi.com
To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease,
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …

[HTML][HTML] GLP-1 receptor agonists in the treatment of type 2 diabetes–state-of-the-art

MA Nauck, DR Quast, J Wefers, JJ Meier - Molecular metabolism, 2021 - Elsevier
Background GLP-1 receptor agonists (GLP-1 RAs) with exenatide bid first approved to treat
type 2 diabetes in 2005 have been further developed to yield effective compounds …

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a …

B Ludvik, F Giorgino, E Jódar, JP Frias, LF Landó… - The Lancet, 2021 - thelancet.com
Background Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide and
GLP-1 receptor agonist under development for the treatment of type 2 diabetes. We aimed to …

The evolving story of incretins (GIP and GLP‐1) in metabolic and cardiovascular disease: a pathophysiological update

MA Nauck, DR Quast, J Wefers… - Diabetes, Obesity and …, 2021 - Wiley Online Library
The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …

Molecular physiology of bile acid signaling in health, disease, and aging

A Perino, H Demagny… - Physiological …, 2021 - journals.physiology.org
Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …

Association of glucagon‐like peptide‐1 receptor agonist treatment with gastric residue in an esophagogastroduodenoscopy

T Kobori, Y Onishi, Y Yoshida, T Tahara… - Journal of diabetes …, 2023 - Wiley Online Library
Abstract Aims/Introduction Previous studies have reported that the glucagon‐like peptide‐1
receptor agonist (GLP‐1RA) delays gastric emptying, and gastric emptying was assessed by …

Regurgitation under anesthesia in a fasted patient prescribed semaglutide for weight loss: a case report

MA Gulak, P Murphy - Canadian Journal of Anesthesia/Journal canadien d' …, 2023 - Springer
Purpose Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) such as semaglutide are a
class of medications prescribed to treat type 2 diabetes mellitus, and more recently, as an …

[HTML][HTML] Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

M Bossart, M Wagner, R Elvert, A Evers, T Hübschle… - Cell metabolism, 2022 - cell.com
Unimolecular triple incretins, combining the activity of glucagon-like peptide-1 (GLP-1),
glucose-dependent insulinotropic polypeptide (GIP), and glucagon (GCG), have …

Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB

RE Steinert, C Feinle-Bisset, L Asarian… - Physiological …, 2017 - journals.physiology.org
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Effects of liraglutide on gastrointestinal functions and weight in obesity: a randomized clinical and pharmacogenomic trial

D Maselli, J Atieh, MM Clark, D Eckert, A Taylor… - …, 2022 - Wiley Online Library
Objective This study aimed to determine the effects of a long‐acting glucagon‐like peptide‐1
(GLP‐1) receptor agonist, liraglutide, and placebo subcutaneously over 16 weeks on weight …