This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Hearing loss caused by exposure to recreational and occupational noise remains a
worldwide disabling condition and dysregulation of redox homeostasis is the hallmark of …

Acute kidney injury is a common complication of rhabdomyolysis. A better understanding of
this syndrome may be useful to identify novel therapeutic targets because there is no …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

Breast cancer (BC) is one of the most common malignant tumors found in females. Previous
studies have demonstrated that curcumin, which is a type of polyphenol compound extracted …

There has been confusion as to what role (s) nitric oxide (NO) has in different physiological
and pathophysiological mechanisms. Some studies imply that NO has cytotoxic properties …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

The heme biosynthetic and catabolic pathways generate pro-and antioxidant compounds,
and consequently, influence cellular sensitivity to oxidants. Heme precursors (δ …

A free radical is any species capable of independent existence that contains one or more
unpaired electrons. Free radical reactions have been implicated in the pathology of more …

Free radicals are molecules which contain one or more unpaired electrons. These
molecules are highly reactive and tend to initiate chain reactions with other molecules also …