The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks

R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

The cross-talk between gut microbiota and lungs in common lung diseases

D Zhang, S Li, N Wang, HY Tan, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
Emerging findings indicate there is a vital cross-talk between gut microbiota and the lungs,
which is known as gut–lung axis. The gut disturbances in lung diseases including allergy …

Thirty years of Lactobacillus rhamnosus GG: a review

L Capurso - Journal of clinical gastroenterology, 2019 - journals.lww.com
Lactobacillus rhamnosus GG (LGG) was the first strain belonging to the genus Lactobacillus
to be patented in 1989 thanks to its ability to survive and to proliferate at gastric acid pH and …

Cardiorespiratory fitness as a predictor of intestinal microbial diversity and distinct metagenomic functions

M Estaki, J Pither, P Baumeister, JP Little, SK Gill… - Microbiome, 2016 - Springer
Background Reduced microbial diversity in human intestines has been implicated in various
conditions such as diabetes, colorectal cancer, and inflammatory bowel disease. The role of …

Microbiome effects on immunity, health and disease in the lung

SD Shukla, KF Budden, R Neal… - Clinical & translational …, 2017 - Wiley Online Library
Chronic respiratory diseases, including asthma, chronic obstructive pulmonary disease
(COPD) and cystic fibrosis (CF), are among the leading causes of mortality and morbidity …

The gut-lung axis in cystic fibrosis

CE Price, GA O'Toole - Journal of bacteriology, 2021 - Am Soc Microbiol
Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

The microbiome in cystic fibrosis pulmonary disease

A Françoise, G Héry-Arnaud - Genes, 2020 - mdpi.com
Cystic fibrosis (CF) is a genetic disease with mutational changes leading to profound
dysbiosis, both pulmonary and intestinal, from a very young age. This dysbiosis plays an …

Impact of CFTR modulation with ivacaftor on gut microbiota and intestinal inflammation

CY Ooi, SA Syed, L Rossi, M Garg, B Needham… - Scientific reports, 2018 - nature.com
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR) gene. Next to progressive airway disease, CF is also associated with …

Gut microbiota in children with cystic fibrosis: a taxonomic and functional dysbiosis

MJ Coffey, S Nielsen, B Wemheuer, NO Kaakoush… - Scientific Reports, 2019 - nature.com
Intestinal dysbiosis has been observed in children with cystic fibrosis (CF), yet the functional
consequences are poorly understood. We investigated the functional capacity of intestinal …

The altered gut microbiota in adults with cystic fibrosis

DG Burke, F Fouhy, MJ Harrison, MC Rea, PD Cotter… - BMC microbiology, 2017 - Springer
Abstract Background Cystic Fibrosis (CF) is an autosomal recessive disease that affects the
function of a number of organs, principally the lungs, but also the gastrointestinal tract. The …