Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

[HTML][HTML] Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides

X Luo, H Chen, Y Song, Z Qin, L Xu, N He, Y Tan… - European Journal of …, 2023 - Elsevier
Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …

AIPs-SnTCN: Predicting anti-inflammatory peptides using fastText and transformer encoder-based hybrid word embedding with self-normalized temporal …

A Raza, J Uddin, A Almuhaimeed, S Akbar… - Journal of chemical …, 2023 - ACS Publications
Inflammation is a biologically resistant response to harmful stimuli, such as infection,
damaged cells, toxic chemicals, or tissue injuries. Its purpose is to eradicate pathogenic …

Peptide-based drug delivery systems

D Berillo, A Yeskendir, Z Zharkinbekov, K Raziyeva… - Medicina, 2021 - mdpi.com
Peptide-based drug delivery systems have many advantages when compared to synthetic
systems in that they have better biocompatibility, biochemical and biophysical properties …

It's getting complicated—a fresh look at p53-MDM2-ARF triangle in tumorigenesis and cancer therapy

CP Kung, JD Weber - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Anti-tumorigenic mechanisms mediated by the tumor suppressor p53, upon oncogenic
stresses, are our bodies' greatest weapons to battle against cancer onset and development …

Traditional and computational screening of non-toxic peptides and approaches to improving selectivity

AA Robles-Loaiza, EA Pinos-Tamayo, B Mendes… - Pharmaceuticals, 2022 - mdpi.com
Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or
diagnostic tools of high therapeutic value. However, only a handful have progressed to the …

Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis

V Pathade, S Nene, S Ratnam, DK Khatri… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …

Repurposed drugs, molecular vaccines, immune‐modulators, and nanotherapeutics to treat and prevent COVID‐19 associated with SARS‐CoV‐2, a deadly …

T Dube, A Ghosh, J Mishra, UB Kompella… - Advanced …, 2021 - Wiley Online Library
The deadly pandemic, coronavirus disease 2019 (COVID‐19), caused due to the severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has paralyzed the world …

Analytical considerations for characterization of generic peptide product: a regulatory insight

A Kuril, K Saravanan, PK Subbappa - Analytical Biochemistry, 2024 - Elsevier
The Peptide therapeutics market was evaluated to be around USD 45.67 BN in 2023 and is
projected to witness massive growth at a CAGR of around 5.63% from 2024 to 2032 (USD …

Sustainable, cost-efficient manufacturing of therapeutic peptides using chemo-enzymatic peptide synthesis (CEPS)

J Pawlas, T Nuijens, J Persson, T Svensson… - Green …, 2019 - pubs.rsc.org
Using a large scale biocatalytic manufacture of the antidiabetic exenatide as an example,
we report that chemo-enzymatic peptide synthesis (CEPS) constitutes an efficient method for …