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[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations
LC Giudice, TT Oskotsky, S Falako… - The FASEB …, 2023 - Wiley Online Library
Endometriosis is a common estrogen‐dependent disorder wherein uterine lining tissue
(endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic …
(endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic …
A review on computer‐aided chemogenomics and drug repositioning for rational COVID‐19 drug discovery
Application of materials capable of energy harvesting to increase the efficiency and
environmental adaptability is sometimes reflected in the ability of discovery of some traces in …
environmental adaptability is sometimes reflected in the ability of discovery of some traces in …
[HTML][HTML] Clofazimine: a journey of a drug
J Xu, A Koval, VL Katanaev - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Among different strategies to develop novel therapies, drug repositioning (aka repurposing)
aims at identifying new uses of an already approved or investigational drug. This approach …
aims at identifying new uses of an already approved or investigational drug. This approach …
[HTML][HTML] Drug repurposing in psoriasis, performed by reversal of disease-associated gene expression profiles
Psoriasis is a skin disease which results in scales on the skin caused by flaky patches.
Psoriasis is triggered by various conditions such as drug reactions, trauma, and skin …
Psoriasis is triggered by various conditions such as drug reactions, trauma, and skin …
Reciprocal enhancement of SARS-CoV-2 and influenza virus replication in human pluripotent stem cell-derived lung organoids
MJ Kim, S Kim, H Kim, D Gil, HJ Han… - Emerging Microbes & …, 2023 - Taylor & Francis
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza
A virus (FLUAV) coinfections were associated with severe respiratory failure and more …
A virus (FLUAV) coinfections were associated with severe respiratory failure and more …
[HTML][HTML] Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid restoration to
prepandemic normality, global mass vaccination is urgently needed. Inducing herd immunity …
prepandemic normality, global mass vaccination is urgently needed. Inducing herd immunity …
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
F Haderk, YT Chou, L Cech… - Nature …, 2024 - nature.com
Targeted therapy is effective in many tumor types including lung cancer, the leading cause
of cancer mortality. Paradigm defining examples are targeted therapies directed against non …
of cancer mortality. Paradigm defining examples are targeted therapies directed against non …
Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS-CoV-2 infectivity
Abstract Recently, COVID-19, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and its variants, caused> 6 million deaths. Symptoms included respiratory …
(SARS-CoV-2) and its variants, caused> 6 million deaths. Symptoms included respiratory …
Identifying therapeutic candidates for endometriosis through a transcriptomics-based drug repositioning approach
Existing medical treatments for endometriosis-related pain are often ineffective,
underscoring the need for new therapeutic strategies. In this study, we applied a …
underscoring the need for new therapeutic strategies. In this study, we applied a …