Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?

T Burnouf, D Strunk, MBC Koh, K Schallmoser - Biomaterials, 2016‏ - Elsevier
The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Placental stem cells

E Antoniadou, AL David - Best Practice & Research Clinical Obstetrics & …, 2016‏ - Elsevier
Highlights•The placenta is a reservoir of stem cells with minimal ethical concerns.•The
placenta is a source of haematopoietic stem cells during fetal development.•The …

Long term effects of the implantation of Wharton's jelly-derived mesenchymal stem cells from the umbilical cord for newly-onset type 1 diabetes mellitus

J Hu, X Yu, Z Wang, F Wang, L Wang, H Gao… - Endocrine …, 2013‏ - jstage.jst.go.jp
1) Stem Cell Research Center, the Affiliated Hospital of Medical College, Qingdao
University, Qingdao 266003, China 2) Endocrinology Department, the Affiliated Hospital of …

Comparative analysis of mesenchymal stem cells cultivated in serum free media

JY Lee, MH Kang, JE Jang, JE Lee, Y Yang, JY Choi… - Scientific reports, 2022‏ - nature.com
Stem cells are attractive candidates for the regeneration of tissue and organ. Mesenchymal
stem cells (MSCs) have been extensively investigated for their potential applications in …

Good manufacturing practice production of human corneal limbus-derived stromal stem cells and in vitro quality screening for therapeutic inhibition of corneal scarring

M Santra, ML Geary, E Rubin, MYS Hsu… - Stem Cell Research & …, 2024‏ - Springer
Background Mesenchymal stem cells in the adult corneal stroma (named corneal stromal
stem cells, CSSCs) inhibit corneal inflammation and scarring and restore corneal clarity in …

Serum-converted platelet lysate can substitute for fetal bovine serum in human mesenchymal stromal cell cultures

MP Mojica-Henshaw, J Morris, L Kelley, J Pierce… - Cytotherapy, 2013‏ - Elsevier
Background aims Fetal bovine serum (FBS) is commonly used as a serum supplement for
culturing human mesenchymal stromal cells (hMSCs). However, human cells grown in FBS …

[HTML][HTML] Molecular and functional characterization of human bone marrow adipocytes

A Poloni, G Maurizi, F Serrani, S Mancini… - Experimental …, 2013‏ - Elsevier
Adipocytes are a cell population largely located in the human bone marrow cavity. In this
specific microenvironment where adipocytes can interact with a variety of different cells, the …

The placenta: applications in orthopaedic sports medicine

JA McIntyre, IA Jones, A Danilkovich… - … American journal of …, 2018‏ - journals.sagepub.com
Background: Placenta has a long history of use for treating burns and wounds. It is a rich
source of collagen and other extracellular matrix proteins, tissue reparative growth factors …

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus‐Derived Mesenchymal Stem Cells for Fetal Tissue …

D Hao, C He, B Ma, L Lankford… - Stem Cells …, 2019‏ - Wiley Online Library
Prenatal stem cell‐based regenerative therapies have progressed substantially and have
been demonstrated as effective treatment options for fetal diseases that were previously …

Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches

C Saury, A Lardenois, C Schleder, I Leroux… - Stem cell research & …, 2018‏ - Springer
Abstract Background Canine MuStem cells have demonstrated regenerative efficacy in a
dog model of muscular dystrophy, and the recent characterization of human counterparts …