One of the most striking patterns of genome structure is the tight, typically negative,
association between transposable elements (TEs) and meiotic recombination rates. While …

Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …

Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …

Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …

Transposable elements (TEs) are ubiquitous genomic parasites. The deleterious
consequences of the presence and activity of TEs have fueled debate about the evolutionary …

PIWI proteins and their guiding Piwi-interacting small RNAs (piRNAs) are crucial for fertility
and transposon defense in the animal germline. In most species, the majority of piRNAs are …

Levels of recombination vary among species, among chromosomes within species, and
among regions within chromosomes in mammals. This heterogeneity may affect levels of …

Background Transposable elements are found in the genomes of nearly all eukaryotes. The
recent completion of the Release 3 euchromatic genomic sequence of Drosophila …

Background Genomic studies of endangered species provide insights into their evolution
and demographic history, reveal patterns of genomic erosion that might limit their viability …

Rapid adaptation of invasive species to novel habitats has puzzled evolutionary biologists
for decades, especially as this often occurs in the face of limited genetic variability. Although …