[HTML][HTML] Decellularised extracellular matrix-based injectable hydrogels for tissue engineering applications

WY Guo, WH Wang, PY Xu… - Biomaterials …, 2024 - pmc.ncbi.nlm.nih.gov
Decellularised extracellular matrix (dECM) is a biomaterial derived from natural tissues that
has attracted considerable attention from tissue engineering researchers due to its …

Learning about liver regeneration from liver-on-a-chip

M Ortega-Ribera - Current Opinion in Biomedical Engineering, 2024 - Elsevier
Liver diseases account for a significant number of deaths worldwide, being largely attributed
to complications of cirrhosis and hepatocellular carcinoma (1). Still, treatment options for …

Designing magnetic microcapsules for cultivation and differentiation of stem cell spheroids

K Gwon, E Dharmesh, KM Nguyen… - Microsystems & …, 2024 - nature.com
Human pluripotent stem cells (hPSCs) represent an excellent cell source for regenerative
medicine and tissue engineering applications. However, there remains a need for robust …

Fully Bioactive Nanodrugs: Stem Cell-Derived Exosomes Engineered with Biomacromolecules to Treat CCl4- and Extreme Hepatectomy-Induced Acute Liver Failure

M Sun, M Li, M Hu, Y Fan, Y Liu, J Sun, J Zhang - ACS nano, 2024 - ACS Publications
Acute liver failure (ALF) is a serious global disease characterized by rapid onset and high
mortality. Currently, the clinical treatment of ALF faces considerable hurdles due to limited …

An Ultrathin Coating of Microcapsules Enhances the Function of Encapsulated Hepatocyte Spheroids

D Choi, K Gwon, JM de Hoyos-Vega… - … Applied Materials & …, 2024 - ACS Publications
Maintaining the differentiated phenotype and function of primary hepatocytes in vitro and in
vivo represents a distinct challenge. Our paper describes microcapsules comprised of a …

Biomimetic Vascularized iPSC‐Hepatocyte Spheroids for Liver Regeneration

J Wang, D Huang, H Ren, Y Zhao - Advanced Science, 2024 - Wiley Online Library
Human induced pluripotent stem cell derived hepatocytes (hiPSC‐heps) hold promising
value for acute liver failure (ALF) treatment, while their therapeutic efficacy is usually limited …

Massive fabrication of functional hepatic cancer spheroids by micropatterned GelMA hydrogel chip for drug screening

F Chen, X Wei, K Chen, L Wang, M Xu - Colloids and Surfaces B …, 2024 - Elsevier
Since hepatic cancer incidence and mortality continue to grow worldwide, it is necessary to
develop the biomimetic tumor models for drug development and tumor therapeutics. Cellular …

Dual Microcapsules Encapsulating Liquid Diamine and Isocyanate for Application in Self-Healing Coatings

H Mu, Y Deng, W Zou, X Yang, Q Zhao - Coatings, 2024 - mdpi.com
Dual microcapsule systems, especially those based on the polyurea matrix, have emerged
as pivotal components driving innovation in self-healing materials, thanks to the intrinsic …