Multimodality imaging probes: design and challenges

A Louie - Chemical reviews, 2010 - ACS Publications
The conundrum of modality selection in clinical diagnostic imaging is that modalities with the
highest sensitivity have relatively poor resolution, while those with high resolution have …

Organic semiconducting luminophores for near‐infrared afterglow, chemiluminescence, and bioluminescence imaging

X Li, C Yin, SS Liew, CS Lee… - Advanced Functional …, 2021 - Wiley Online Library
Optical imaging has played a pivotal role in deciphering in vivo bioinformatics but is limited
by shallow penetration depth and poor imaging performance owing to interfering tissue …

[HTML][HTML] The bone microenvironment invigorates metastatic seeds for further dissemination

W Zhang, IL Bado, J Hu, YW Wan, L Wu, H Wang… - Cell, 2021 - cell.com
Metastasis has been considered as the terminal step of tumor progression. However, recent
genomic studies suggest that many metastases are initiated by further spread of other …

Targeted superparamagnetic iron oxide nanoparticles for early detection of cancer: Possibilities and challenges

Z Bakhtiary, AA Saei, MJ Hajipour, M Raoufi… - … , Biology and Medicine, 2016 - Elsevier
Nanomedicine, the integration of nanotechnological tools in medicine demonstrated
promising potential to revolutionize the diagnosis and treatment of various human health …

Design and development of molecular imaging probes

K Chen, X Chen - Current topics in medicinal chemistry, 2010 - ingentaconnect.com
Molecular imaging, the visualization, characterization and measurement of biological
processes at the cellular, subcellular level, or even molecular level in living subjects, has …

'Two is better than one'—probes for dual-modality molecular imaging

LE Jennings, NJ Long - Chemical communications, 2009 - pubs.rsc.org
Molecular or personalised medicine is the future of patient management and healthcare,
and molecular imaging plays a key role towards this goal. However, amongst molecular …

In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals

DM Close, T Xu, GS Sayler, S Ripp - Sensors, 2010 - mdpi.com
In vivo bioluminescent imaging (BLI) is increasingly being utilized as a method for modern
biological research. This process, which involves the noninvasive interrogation of living …

Expanding theranostic radiopharmaceuticals for tumor diagnosis and therapy

C Barca, CM Griessinger, A Faust, D Depke, M Essler… - Pharmaceuticals, 2021 - mdpi.com
Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and
molecular imaging (MI), including positron emission tomography (PET), single-photon …

Photoacoustic tomography: fundamentals, advances and prospects

J Yao, LV Wang - Contrast media & molecular imaging, 2011 - Wiley Online Library
Optical microscopy has been contributing to the development of life science for more than
three centuries. However, due to strong optical scattering in tissue, its in vivo imaging ability …

Hybrid PET-optical imaging using targeted probes

M Nahrendorf, E Keliher, B Marinelli… - Proceedings of the …, 2010 - pnas.org
Fusion imaging of radionuclide-based molecular (PET) and structural data [x-ray computed
tomography (CT)] has been firmly established. Here we show that optical measurements …