Advances in coupling microfluidic chips to mass spectrometry

X Feng, BF Liu, J Li, X Liu - Mass spectrometry reviews, 2015 - Wiley Online Library
Microfluidic technology has shown advantages of low sample consumption, reduced
analysis time, high throughput, and potential for integration and automation. Coupling …

Silicon‐based laser desorption ionization mass spectrometry for the analysis of biomolecules: a progress report

SA Iakab, P Rafols, M García‐Altares… - Advanced Functional …, 2019 - Wiley Online Library
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) is widely used
in the biomedical field for the label‐free analysis of molecules such as drugs, lipids …

Effective enrichment and detection of trace polycyclic aromatic hydrocarbons in food samples based on magnetic covalent organic framework hybrid microspheres

N Li, D Wu, N Hu, G Fan, X Li, J Sun… - Journal of agricultural …, 2018 - ACS Publications
The present study reported a facile, sensitive, and efficient method for enrichment and
determination of trace polycyclic aromatic hydrocarbons (PAHs) in food samples by …

Conjugated microporous polymers with built-in magnetic nanoparticles for excellent enrichment of trace hydroxylated polycyclic aromatic hydrocarbons in human …

L Zhou, Y Hu, G Li - Analytical Chemistry, 2016 - ACS Publications
Conjugated microporous polymers (CMPs), linked by a covalent bond to form an extension
of the aromatic ring skeleton, are microporous materials characterized by a highly …

Rapid and label-free optical assay of S-layer protein with high sensitivity using TiO2-coated porous silicon-based microfluidic biosensor

S Zhuo, M Xun, M Li, X Kong, R Shao, T Zheng… - Sensors and Actuators B …, 2020 - Elsevier
S-layer protein (SLP) is a surface protein present in many bacteria and shows unique self-
assemble ability for various applications, but its detection methods are very limited. In this …

Surface plasmon resonance imaging in arrays coupled with mass spectrometry (SUPRA–MS): proof of concept of on-chip characterization of a potential breast cancer …

F Remy-Martin, M El Osta, G Lucchi, R Zeggari… - Analytical and …, 2012 - Springer
Protein biomarker discovery and validation are crucial for diagnosis, prognosis, and
theranostics of human pathologies;“omics” approaches bring new insights in this field. In …

Highly sensitive thrombin detection by matrix assisted laser desorption ionization-time of flight mass spectrometry with aptamer functionalized core–shell Fe3O4@ C …

X Zhang, S Zhu, C Deng, X Zhang - Talanta, 2012 - Elsevier
Here, we describe a sensitive and specific method for thrombin detection with aptamer
functionalized core–shell Fe3O4@ C@ Au magnetic microspheres (Au-MMPs). Firstly, Au …

Mass-tag enhanced immuno-laser desorption/ionization mass spectrometry for sensitive detection of intact protein antigens

M Lorey, B Adler, H Yan, R Soliymani… - Analytical …, 2015 - ACS Publications
A new read-out method for antibody arrays using laser desorption/ionization-mass
spectrometry (LDI-MS) is presented. Small, photocleavable reporter molecules with a …

Current development of microfluidic immunosensing approaches for mycotoxin detection via capillary electromigration and lateral flow technology

P Li, Z Zhang, Q Zhang, N Zhang, W Zhang… - …, 2012 - Wiley Online Library
Mycotoxin contamination in the food chain has caused serious health issues in humans and
animals. Thus, a rapid on‐site and lab‐independent detection method for mycotoxins, such …

Enrichment and quantitative determination of 5-(hydroxymethyl)-2′-deoxycytidine, 5-(formyl)-2′-deoxycytidine, and 5-(carboxyl)-2′-deoxycytidine in human urine …

M Guo, L Zhang, Y Du, W Du, D Liu, C Guo… - Analytical …, 2018 - ACS Publications
5-(Hydroxymethyl)-2′-deoxycytidine (5-hmdC), 5-(formyl)-2′-deoxycytidine (5-fodC), and
5-(carboxyl)-2′-deoxycytidine (5-cadC) are crucial intermediate products of the DNA …