Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Background Exercise changes the concentrations of many metabolites, which are small
molecules (< 1.5 kDa) metabolized by the reactions of human metabolism. In recent years …

Physical activity (PA) and exercise are among the most important determinants of health.
However, PA is a complex and heterogeneous behavior and the biological mechanisms …

Background: The effectiveness of blood flow restriction training (BFRT) as compared with
other forms of training, such as resistance training, has been evaluated in the literature in …

This systematic review provides a qualitative appraisal of 24 high-quality metabolomics-
based studies published over the past decade exploring exercise-induced alterations of the …

Succinate is released by skeletal muscle during exercise and activates SUCNR1/GPR91.
Signaling of SUCNR1 is involved in metabolite-sensing paracrine communication in skeletal …

Emoxypine (ethylmethylhydroxypyridine) is a synthetic derivative of vitamin B6. Emoxypine
succinate is a registered drug in Russia and Ukraine under various trade names including …

Purpose: High cardiorespiratory capacity is a key determinant of human performance and
life expectancy; however, the underlying mechanisms are not fully understood. The objective …

Triage and medical intervention strategies for unanticipated exposure during a radiation
incident benefit from the early, rapid and accurate assessment of dose level. Radiation …

Clinical lipidomics using mass spectrometry (MS) is important to support discovery of
biomarkers for diagnosis and understanding the pathophysiology of diseases. Frequently …