Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …

Messenger RNA processing and decay is a key mechanism to control gene expression at
the post-transcriptional level in response to ever-changing environmental conditions. In this …

How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …

New antibiotics are urgently needed to address the mounting resistance challenge. In early
drug discovery, one of the bottlenecks is the elucidation of targets and mechanisms. To …

Engineering strategies to improve terpenoids' production in Bacillus subtilis mainly focus on
2 C-methyl-d-erythritol-4-phosphate (MEP) pathway overexpression. To systematically …

Small open reading frame encoded proteins (SEPs) gained increasing interest during the
last few years because of their broad range of important functions in both prokaryotes and …

Taxonomically restricted genes (TRGs) are unique for a defined group of organisms and
may act as potential genetic determinants of lineage-specific, biological properties. Here, we …

Proteogenomics combines proteomics, genomics, and transcriptomics and has considerably
improved genome annotation in poorly investigated phylogenetic groups for which …

The near‐minimal bacterium Mesoplasma florum is an interesting model for synthetic
genomics and systems biology due to its small genome (~ 800 kb), fast growth rate, and lack …

Cyanobacteria, the evolutionary ancestors of plant chloroplasts, contribute substantially to
the Earth's biogeochemical cycles and are of great interest for a sustainable economy …