Opportunities and challenges of the human microbiome in ovarian cancer

H Cheng, Z Wang, L Cui, Y Wen, X Chen… - Frontiers in …, 2020 - frontiersin.org
Ovarian cancer is the most lethal malignancy among gynecological cancers worldwide. Most
ovarian cancer patients are diagnosed at an advanced stage because of non-specific …

Neuroprotective effect of glycosides in Buyang Huanwu Decoction on pyroptosis following cerebral ischemia-reperfusion injury in rats

Y She, L Shao, Y Zhang, Y Hao, Y Cai, Z Cheng… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Buyang Huanwu Decoction (BYHWD) is used in
classical traditional Chinese medicine to prevent and treat cerebral ischemia. Glycosides …

Oncogenic roles and related mechanisms of the long non-coding RNA MINCR in human cancers

C Chao, R Tang, J Zhao, D Di, Y Qian… - Frontiers in cell and …, 2023 - frontiersin.org
Long non-coding RNAs (lncRNAs) play vital roles in regulating epigenetic mechanisms and
gene expression levels, and their dysregulation is closely associated with a variety of …

A novel lncRNA‐LINC01116 regulates tumorigenesis of glioma by targeting VEGFA

J Ye, J Zhu, H Chen, J Qian, L Zhang… - … journal of cancer, 2020 - Wiley Online Library
Brain glioma is the most common malignant tumor of the central nervous system, and one of
the leading causes of death in patients with intracranial tumors. The clinical outcome of …

MCC950 alleviates seizure severity and angiogenesis by inhibiting NLRP3/IL-1β signaling pathway-mediated pyroptosis in mouse model of epilepsy

Y Hong, C Wei, M Fu, X Li, H Zhang, B Yao - International …, 2024 - Elsevier
Epilepsy is one of the most common serious chronic brain disorders, affecting up to 70
million people worldwide. Vascular disruption, including blood–brain barrier impairment and …

The beta-hydroxybutyrate suppresses the migration of glioma cells by inhibition of NLRP3 inflammasome

S Shang, L Wang, Y Zhang, H Lu, X Lu - Cellular and molecular …, 2018 - Springer
Activation of inflammasome leads to the formation of an inflammatory microenvironment
which plays an important role in the process of cancer development. Beta-hydroxybutyrate …

Identification of latent biomarkers in connection with progression and prognosis in oral cancer by comprehensive bioinformatics analysis

A Reyimu, Y Chen, X Song, W Zhou, J Dai… - World Journal of Surgical …, 2021 - Springer
Background Oral cancer (OC) is a common and dangerous malignant tumor with a low
survival rate. However, the micro level mechanism has not been explained in detail …

Comprehensive analysis of pyroptosis-associated in molecular classification, immunity and prognostic of glioma

P Chen, Y Li, N Li, L Shen, Z Li - Frontiers in Genetics, 2022 - frontiersin.org
Integrative analysis was performed in the Chinese Glioma Genome Atlas and The Cancer
Genome Atlas to describe the pyroptosis-associated molecular classification and prognostic …

PSMB8 inhibition decreases tumor angiogenesis in glioblastoma through vascular endothelial growth factor A reduction

HH Chang, YC Cheng, WC Tsai, Y Chen - Cancer science, 2020 - Wiley Online Library
Glioblastoma, also known as glioblastoma multiforme (GBM), is a fast‐growing tumor and
the most aggressive brain malignancy. Proteasome subunit beta type‐8 (PSMB8) is one of …

Caspase-4 in glioma indicates deterioration and unfavorable prognosis by affecting tumor cell proliferation and immune cell recruitment

L Di, M Li, X Lei, W **e, G Liu, Y Wang, W Zhang… - Scientific Reports, 2024 - nature.com
Gliomas are the most common malignant tumors of the central nervous system, accounting
for approximately 80% of all malignant brain tumors. Accumulating evidence suggest that …