Sexual dimorphisms account for differences in clinical manifestations or incidence of
infectious or autoimmune diseases and malignancy between females and males. Females …

Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …

Neutrophil extracellular traps (NETs) are implicated in autoimmunity, but how they are
generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune …

Neutrophils are the most abundant, short lived, and terminally differentiated leukocytes with
distinct tiers of arsenals to counter pathogens. Neutrophils were traditionally considered …

Neutrophils have long been considered simple suicide killers at the bottom of the hierarchy
of the immune response. That view began to change 10–20 yr ago, when the sophisticated …

Of all cells implicated in the pathology of rheumatoid arthritis (RA), neutrophils possess the
greatest cytotoxic potential, owing to their ability to release degradative enzymes and …

Recent data suggest that NETosis plays a crucial role in the innate immune response and
disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell …

Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

Neutrophils are best known for their critical role in host defense, for which they utilize
multiple innate immune mechanisms, including microbe-associated pattern recognition …

Oxidative stress is increased in systemic lupus erythematosus (SLE), and it contributes to
immune system dysregulation, abnormal activation and processing of cell-death signals …