Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause
severe invasive infections upon ingestion with contaminated food. Clinically, listerial …

The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system
(CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the …

Intractable infected microenvironments caused by drug‐resistant bacteria stalls the normal
course of wound healing. Sono‐piezodynamic therapy (SPT) is harnessed to combat …

Background Although meningitis is largely preventable, it still causes hundreds of thousands
of deaths globally each year. WHO set ambitious goals to reduce meningitis cases by 2030 …

Progress has been made in the prevention and treatment of community-acquired bacterial
meningitis during the past three decades but the burden of the disease remains high …

CRISPR-Cas systems have been employed to detect a large variety of pathogenic
microorganisms by simply changing the guide RNA sequence. However, these platforms …

To eliminate multidrug-resistant bacteria of Acinetobacter baumannii, we screened 1100
Food and Drug Administration–approved small molecule drugs and accessed the …

Background Streptococcus pneumoniae meningitis is a serious inflammatory disease of the
central nervous system (CNS) and is associated with high morbidity and mortality rates. The …

Intensive care units constitute a critical setting for the management of infections. The
patients' fragilities and spread of multidrug-resistant microorganisms lead to relevant …

Background The epidemiology of acute bacterial meningitis has changed substantially since
the introduction of conjugate vaccines. Methods We analyzed nationwide surveillance data …