Mitochondria are best known for harboring pathways involved in ATP synthesis through the
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …

Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are morpho-functional
units, formed at the loci of close apposition of the ER-forming endomembrane and outer …

Nearly all mitochondrial proteins are encoded by the nuclear genome and imported into
mitochondria after synthesis on cytosolic ribosomes. These precursor proteins are …

In Gram-negative bacteria, the biogenesis of β-barrel outer membrane proteins is mediated
by the β-barrel assembly machinery (BAM). The mechanism employed by BAM is complex …

The outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts all contain
transmembrane β-barrel proteins. These β-barrel proteins serve essential functions in cargo …

Glutathione is an important mediator and regulator of cellular redox processes. Detailed
knowledge of local glutathione redox potential (EGSH) dynamics is critical to understand the …

Apoptosis acts in defense against microbial infection, and many infectious agents have
developed strategies to inhibit host cell apoptosis. The human pathogen Chlamydia …

Mitochondria are the central hub of key cellular processes such as energy conversion, cell
signaling, cell cycle regulation and cell differentiation. Therefore, in particular, mitochondrial …

The mitochondrial outer membrane harbors two protein translocases that are essential for
cell viability: the translocase of the outer mitochondrial membrane (TOM) and the sorting and …

Abstract β‐Barrel proteins found in the outer membrane of Gram‐negative bacteria serve a
variety of cellular functions. Proper folding and assembly of these proteins are essential for …