Blood–brain barrier (BBB) interface with multicellular structure controls strictly the entry of
varied circulating macromolecules from the blood-facing surface into the brain parenchyma …

Huntington's disease (HD) is one of neurodegenerative diseases, and is defined as a
monogenetic disease due to the mutation of Huntingtin gene. This disease affects several …

Objective To assess the prevalence, timing, and functional impact of psychiatric, cognitive,
and motor abnormalities in Huntington disease (HD) gene carriers, we analyzed …

Background and purpose Cognitive impairment is a central feature of Huntington's disease
(HD), but it is unclear to what extent more aggressive cognitive phenotypes exist in HD …

Introduction Huntington's disease (HD) is a rare autosomal dominant neurodegenerative
disorder caused by a CAG expansion greater than 35 in the IT-15 gene. There is an inverse …

Abstract Background Neurofilament light protein (NfL) has been proven to be a sensitive
biomarker for Huntington's disease (HD). However, these studies did not include HD …

Abstract Background Latin America has played a crucial role in advancing our
understanding of Huntington's disease (HD). However, previous global reviews include …

Background and purpose Huntington's disease (HD) is an autosomal dominant condition
caused by CAG‐triplet repeat expansions. CAG‐triplet repeat expansion is inversely …

Background: Older patients with Huntington's disease (HD) are often thought to have a
slower progressing disease course with less behavioral symptoms than younger patients …

Huntington's disease is associated with motor, cognitive and behavioral dysfunction.
Behavioral symptoms may present before, after, or simultaneously with clinical disease …