Ageing in the brain: mechanisms and rejuvenating strategies
Ageing is characterized by the progressive loss of cellular homeostasis, leading to an
overall decline of the organism's fitness. In the brain, ageing is highly associated with …
overall decline of the organism's fitness. In the brain, ageing is highly associated with …
How do neurons age? A focused review on the aging of the microtubular cytoskeleton
B Richardson, T Goedert, S Quraishe… - Neural Regeneration …, 2024 - journals.lww.com
Aging is the leading risk factor for Alzheimer's disease and other neurodegenerative
diseases. We now understand that a breakdown in the neuronal cytoskeleton, mainly …
diseases. We now understand that a breakdown in the neuronal cytoskeleton, mainly …
Raman Spectroscopy in Cellular and Tissue Aging Research
The establishment of various molecular, physiological, and genetic markers for cellular
senescence and aging‐associated conditions has progressed the aging study. To identify …
senescence and aging‐associated conditions has progressed the aging study. To identify …
Age‐specific and compartment‐dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons
JN Sleigh, F Mattedi, S Richter, E Annuario, K Ng… - Aging …, 2024 - Wiley Online Library
Mitochondria are dynamic bioenergetic hubs that become compromised with age. In
neurons, declining mitochondrial axonal transport has been associated with reduced …
neurons, declining mitochondrial axonal transport has been associated with reduced …
Identifying optimal reference genes for real-time quantitative polymerase chain reaction in human myocardial tissues
M Camacho-Encina, LK Booth… - Cardiovascular …, 2024 - academic.oup.com
Identifying optimal reference genes for real-time quantitative polymerase chain reaction in
human myocardial tissues | Cardiovascular Research | Oxford Academic Skip to Main Content …
human myocardial tissues | Cardiovascular Research | Oxford Academic Skip to Main Content …
Caliber of zebrafish touch-sensory axons is dynamic in vivo
K Ching, A Sagasti - bioRxiv, 2024 - biorxiv.org
Cell shape is crucial to cell function, particularly in neurons. The cross-sectional diameter,
also known as caliber, of axons and dendrites is an important parameter of neuron shape …
also known as caliber, of axons and dendrites is an important parameter of neuron shape …
Using an in-vivo Drosophila model to determine the influence of age and hyperphosphorylated tau on neuronal structure and function
B Richardson - 2024 - eprints.soton.ac.uk
Although ageing is considered the leading risk factor for Alzheimer's Disease (AD),
knowledge of what occurs to neuronal morphology and cytoskeletal structures during …
knowledge of what occurs to neuronal morphology and cytoskeletal structures during …
Characterisation of the mechano-chemical relationship between actin and microtubule cytoskeletons and the active motion of cytoplasmic components
L Al-Khatib - 2024 - qmro.qmul.ac.uk
The advancements in imaging techniques have markedly enhanced the ability to observe
and reconstruct dynamic cellular processes, thereby deepening our understanding of cell …
and reconstruct dynamic cellular processes, thereby deepening our understanding of cell …
[CITATION][C] 神经元是如何衰老的? 微管细胞骨架老化研究综述
B Richardson, T Goedert, S Quraishe, K Deinhardt… - **神经再生研究 (英文版), 2024