Ageing in the brain: mechanisms and rejuvenating strategies

F Gaspar-Silva, D Trigo, J Magalhaes - Cellular and Molecular Life …, 2023 - Springer
Ageing is characterized by the progressive loss of cellular homeostasis, leading to an
overall decline of the organism's fitness. In the brain, ageing is highly associated with …

How do neurons age? A focused review on the aging of the microtubular cytoskeleton

B Richardson, T Goedert, S Quraishe… - Neural Regeneration …, 2024 - journals.lww.com
Aging is the leading risk factor for Alzheimer's disease and other neurodegenerative
diseases. We now understand that a breakdown in the neuronal cytoskeleton, mainly …

Raman Spectroscopy in Cellular and Tissue Aging Research

JH Kim, D Yang, S Park - Aging Cell, 2025 - Wiley Online Library
The establishment of various molecular, physiological, and genetic markers for cellular
senescence and aging‐associated conditions has progressed the aging study. To identify …

Age‐specific and compartment‐dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons

JN Sleigh, F Mattedi, S Richter, E Annuario, K Ng… - Aging …, 2024 - Wiley Online Library
Mitochondria are dynamic bioenergetic hubs that become compromised with age. In
neurons, declining mitochondrial axonal transport has been associated with reduced …

Identifying optimal reference genes for real-time quantitative polymerase chain reaction in human myocardial tissues

M Camacho-Encina, LK Booth… - Cardiovascular …, 2024 - academic.oup.com
Identifying optimal reference genes for real-time quantitative polymerase chain reaction in
human myocardial tissues | Cardiovascular Research | Oxford Academic Skip to Main Content …

Caliber of zebrafish touch-sensory axons is dynamic in vivo

K Ching, A Sagasti - bioRxiv, 2024 - biorxiv.org
Cell shape is crucial to cell function, particularly in neurons. The cross-sectional diameter,
also known as caliber, of axons and dendrites is an important parameter of neuron shape …

Using an in-vivo Drosophila model to determine the influence of age and hyperphosphorylated tau on neuronal structure and function

B Richardson - 2024 - eprints.soton.ac.uk
Although ageing is considered the leading risk factor for Alzheimer's Disease (AD),
knowledge of what occurs to neuronal morphology and cytoskeletal structures during …

Characterisation of the mechano-chemical relationship between actin and microtubule cytoskeletons and the active motion of cytoplasmic components

L Al-Khatib - 2024 - qmro.qmul.ac.uk
The advancements in imaging techniques have markedly enhanced the ability to observe
and reconstruct dynamic cellular processes, thereby deepening our understanding of cell …

[CITATION][C] 神经元是如何衰老的? 微管细胞骨架老化研究综述

B Richardson, T Goedert, S Quraishe, K Deinhardt… - **神经再生研究 (英文版), 2024