The pathogenesis of allergic diseases entails an ineffective tolerogenic immune response to
allergens. Regulatory T (Treg) cells play a key role in sustaining immune tolerance to …

Tumours express a range of antigens, including self-antigens. Regulatory T cells are crucial
for maintaining T-cell tolerance to self-antigens. Regulatory T cells are thought to dampen T …

The immune system of patients infected by SARS-CoV-2 is severely impaired. Detailed
investigation of T cells and cytokine production in patients affected by COVID-19 pneumonia …

Regulatory T (Treg) cells mediate homeostatic peripheral tolerance by suppressing
autoreactive T cells. Failure of host antitumor immunity may be caused by exaggerated …

It is well known that many tumours are potentially immunogenic, as corroborated by the
presence of tumour-specific immune responses in vivo. Nonetheless, spontaneous …

Forming the outer body barrier, our skin is permanently exposed to pathogens and
environmental hazards. Therefore, skin diseases are among the most common disorders. In …

Mesenchymal stem cells (MSCs) are largely studied for their potential clinical use. Recently,
they have gained further interest after demonstration of an immunosuppressive role. In this …

Tumor-associated macrophages are a prominent component of ovarian cancer stroma and
contribute to tumor progression. B7-H4 is a recently identified B7 family molecule. We show …

Reactive oxygen species (ROS)‐induced oxidative stress in the endoplasmic reticulum (ER)
is generally believed to be an important prerequisite for immunogenic cell death (ICD) which …

Several lines of evidence suggest that multiple sclerosis (MS), like other autoimmune
diseases, may be triggered by microbial infections. Pathogens associated with development …