Cellular responses to TNF are inherently heterogeneous within an isogenic cell population
and across different cell types. TNF promotes cell survival by activating pro-inflammatory NF …

Bacterial growth presents many beautiful phenomena that pose new theoretical challenges
to statistical physicists, and are also amenable to laboratory experimentation. This review …

We present a whole-cell fully dynamical kinetic model (WCM) of JCVI-syn3A, a minimal cell
with a reduced genome of 493 genes that has retained few regulatory proteins or small …

The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect
prescription and use of antibiotics. A core problem is that there is no sufficiently fast …

Evolutionarily divergent bacteria share a common phenomenological strategy for cell-size
homeostasis under steady-state conditions. In the presence of inherent physiological …

INTRODUCTION The generation of biological data is presenting us with one of the most
demanding analysis challenges the world has ever faced, not only in terms of storage and …

Dielectric metasurfaces support resonances that are widely explored both for far-field
wavefront sha** and for near-field sensing and imaging. Their design explores the …

Organisms determine the transcription rates of thousands of genes through a few modes of
regulation that recur across the genome. In bacteria, the relationship between the regulatory …

Despite decades of research, how mammalian cell size is controlled remains unclear
because of the difficulty of directly measuring growth at the single-cell level. Here we report …

It is generally assumed that the allocation and synthesis of total cellular resources in
microorganisms are uniquely determined by the growth conditions. Adaptation to a new …