C-reactive protein as a biomarker for major depressive disorder?
L Orsolini, S Pompili, S Tempia Valenta, V Salvi… - International journal of …, 2022 - mdpi.com
The etiopathogenesis of depression is not entirely understood. Several studies have
investigated the role of inflammation in major depressive disorder. The present work aims to …
investigated the role of inflammation in major depressive disorder. The present work aims to …
Neuroinflammation and oxidative stress in psychosis and psychosis risk
Although our understanding of psychotic disorders has advanced substantially in the past
few decades, very little has changed in the standard of care for these illnesses since the …
few decades, very little has changed in the standard of care for these illnesses since the …
Protein-C reactive as biomarker predictor of schizophrenia phases of illness? A systematic review
L Orsolini, F Sarchione, F Vellante… - Current …, 2018 - ingentaconnect.com
Background: Schizophrenia is a complex illness in which genetic, environmental, and
epigenetic components have been implicated. However, recently, psychiatric disorders …
epigenetic components have been implicated. However, recently, psychiatric disorders …
COVID-19. Pandemic surgery guidance
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity
D Chatterjee, JM Beaulieu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Inhibition of Glycogen synthase kinase 3 (GSK3) is a popular explanation for the effects of
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
Mitochondrial dysfunction in schizophrenia
P Ni, S Chung - BioEssays, 2020 - Wiley Online Library
Schizophrenia (SCZ) is a severe neurodevelopmental disorder affecting 1% of populations
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …
Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and …
We compared transcriptomic profiles of cerebral organoids differentiated from induced
pluripotent stem cells of eight schizophrenia and eight bipolar disorder patients to identify …
pluripotent stem cells of eight schizophrenia and eight bipolar disorder patients to identify …
The complex interaction of mitochondrial genetics and mitochondrial pathways in psychiatric disease
While accounting for only 2% of the body's weight, the brain utilizes up to 20% of the body's
total energy. Not surprisingly, metabolic dysfunction and energy supply-and-demand …
total energy. Not surprisingly, metabolic dysfunction and energy supply-and-demand …
Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes
Aims/hypothesis Psychiatric disorders, such as schizophrenia (SCZ), major depressive
disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes …
disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes …
Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells
S Michels, GK Ganjam, H Martins, GM Schratt… - Cell death …, 2018 - nature.com
Affective disorders such as major depression and bipolar disorder are among the most
prevalent forms of mental illness and their etiologies involve complex interactions between …
prevalent forms of mental illness and their etiologies involve complex interactions between …