The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function

RR Llinás - Science, 1988 - science.org
This article reviews the electroresponsive properties of single neurons in the mammalian
central nervous system (CNS). In some of these cells the ionic conductances responsible for …

Molecular physiology of cardiac repolarization

JM Nerbonne, RS Kass - Physiological reviews, 2005 - journals.physiology.org
The heart is a rhythmic electromechanical pump, the functioning of which depends on action
potential generation and propagation, followed by relaxation and a period of refractoriness …

Multiple types of neuronal calcium channels and their selective modulation

RW Tsien, D Lipscombe, DV Madison, KR Bley… - Trends in …, 1988 - cell.com
Voltage-gated Ca e+ channels control the entry of Ca e+ ions across the surface membrane
of neurons and other cells and thereby influence electrical activity and diverse cellular …

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell

L Conti, SM Pollard, T Gorba, E Reitano, M Toselli… - PLoS …, 2005 - journals.plos.org
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical
divisions. In vivo, however, stem cells are generally thought to depend on specialised …

[HTML][HTML] Ion channels in the heart

DC Bartos, E Grandi, CM Ripplinger - Comprehensive physiology, 2015 - ncbi.nlm.nih.gov
Optimal cardiac function depends on proper timing of excitation and contraction in various
regions of the heart, as well as on appropriate heart rate. This is accomplished via …

A novel T-type current underlies prolonged Ca (2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus

JR Huguenard, DA Prince - Journal of Neuroscience, 1992 - Soc Neuroscience
The inhibitory GABAergic projection of thalamic nucleus reticularis (nRt) neurons onto
thalamocortical relay cells (TCs) is important in generating the normal thalamocortical …

A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system

U Misgeld, M Bijak, W Jarolimek - Progress in neurobiology, 1995 - Elsevier
The inhibitory neurotransmitter GABA acts in the mammalian brain through two different
receptor classes: GABAA and GABAB receptors. GABAB receptors differ fundamentally from …

Calcium currents in rat thalamocortical relay neurones: kinetic properties of the transient, low‐threshold current.

DA Coulter, JR Huguenard… - The Journal of …, 1989 - Wiley Online Library
1. Calcium currents were recorded with whole‐cell voltage‐clamp procedures in relay
neurones of the rat thalamus which had been acutely isolated by an enzymatic dissociation …

Pharmacological Properties of T-Type Ca2+ Current in Adult Rat Sensory Neurons: Effects of Anticonvulsant and Anesthetic Agents

SM Todorovic, CJ Lingle - Journal of neurophysiology, 1998 - journals.physiology.org
Todorovic, Slobodan M. and Christopher J. Lingle. Pharmacological properties of T-type
Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. J …

Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum

CD Aizenman, DJ Linden - Journal of neurophysiology, 1999 - journals.physiology.org
Current-clamp recordings were made from the deep cerebellar nuclei (DCN) of 12-to 15-day-
old rats to understand the factors that mediate intrinsic spontaneous firing patterns. All of the …