Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis

GS De Pablo, J Radua, J Pereira, I Bonoldi… - JAMA …, 2021 - jamanetwork.com
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

The temporal dynamics of transition to psychosis in individuals at clinical high-risk (CHR-P) shows negative prognostic effects of baseline antipsychotic exposure: a …

A Raballo, M Poletti, A Preti - Translational Psychiatry, 2023 - nature.com
Meta-analytic evidence indicates that baseline exposure to antipsychotics (AP) in individuals
at clinical high-risk for psychosis (CHR-P) is associated with an even higher risk of transition …

Establishing a clinical service to prevent psychosis: what, how and when? Systematic review

G Salazar de Pablo, A Estradé, M Cutroni… - Translational …, 2021 - nature.com
The first rate-limiting step to successfully translate prevention of psychosis in to clinical
practice is to establish specialised Clinical High Risk for Psychosis (CHR-P) services. This …

Meta-analysis of the effects of microplastic on fish: Insights into growth, survival, reproduction, oxidative stress, and gut microbiota diversity

J Wang, F Wu, S Dong, X Wang, S Ai, Z Liu, X Wang - Water Research, 2024 - Elsevier
Aquatic ecosystems are primary repositories for microplastics (MPs), which pose significant
risks to aquatic organisms. This study addresses the gap in understanding the effects of MPs …

Reducing the duration of untreated psychosis (DUP) in a US community: a quasi-experimental trial

VH Srihari, M Ferrara, F Li, E Kline… - Schizophrenia …, 2022 - academic.oup.com
Abstract Objective Duration of Untreated Psychosis (DUP) remains unacceptably long and
limits effectiveness of care. To determine whether an early detection campaign (“Mindmap”) …

Prediction and prevention in the clinical high-risk for psychosis paradigm: a review of the current status and recommendations for future directions of inquiry

MA Worthington, TD Cannon - Frontiers in psychiatry, 2021 - frontiersin.org
Prediction and prevention of negative clinical and functional outcomes represent the two
primary objectives of research conducted within the clinical high-risk for psychosis (CHR-P) …

Baseline benzodiazepine exposure is associated with greater risk of transition in clinical high-risk for psychosis (CHR-P): a meta-analysis

A Raballo, M Poletti, A Preti - Psychological Medicine, 2023 - cambridge.org
BackgroundEmerging meta-analytical evidence indicates that baseline exposure to
antipsychotics and to antidepressants in individuals at clinical high-risk for psychosis (CHR …

Meta-analyzing the prevalence and prognostic effect of antipsychotic exposure in clinical high-risk (CHR): when things are not what they seem

A Raballo, M Poletti, A Preti - Psychological Medicine, 2020 - cambridge.org
BackgroundThe clinical high-risk (CHR) for psychosis paradigm is changing psychiatric
practice. However, a widespread confounder, ie baseline exposure to antipsychotics (AP) in …

Real-world long-term outcomes in individuals at clinical risk for psychosis: the case for extending duration of care

P Fusar-Poli, A De Micheli, L Signorini, H Baldwin… - …, 2020 - thelancet.com
Background Most services for individuals at Clinical High Risk for Psychosis (CHR-P)
provide short-term clinical care. This study determines the real-world and long-term clinical …

Network meta-analysis indicates superior effects of omega-3 polyunsaturated fatty acids in preventing the transition to psychosis in individuals at clinical high-risk

C Chen, Y Deng, Y Li, M Zhang, T Yu… - International Journal …, 2024 - academic.oup.com
Background The efficacy of pharmacological and nutritional interventions in individuals at
clinical high risk for psychosis (CHR-P) remains elusive. This study aims to investigate the …