Domestication explains two-thirds of differential-gene-expression variance between domestic and wild animals; the remaining one-third reflects intraspecific and …

I Chadaeva, P Ponomarenko, R Kozhemyakina… - Animals, 2021 - mdpi.com
Simple Summary Before genomes were sequenced, zoologists had discovered destabilizing
selection as a general pattern of animal domestication that in foxes and minks had yielded …

Natural Selection Equally Supports the Human Tendencies in Subordination and Domination: A Genome-Wide Study With in silico Confirmation and in vivo …

I Chadaeva, P Ponomarenko, D Rasskazov… - Frontiers in …, 2019 - frontiersin.org
We proposed the following heuristic decision-making rule:“IF {an excess of a protein relating
to the nervous system is an experimentally known physiological marker of low pain …

Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication …

M Ponomarenko, M Kleshchev, P Ponomarenko… - BMC genetics, 2020 - Springer
Background In population ecology, the concept of reproductive potential denotes the most
vital indicator of chances to produce and sustain a healthy descendant until his/her …

A bioinformatics model of human diseases on the basis of differentially expressed genes (of domestic versus wild animals) that are orthologs of human genes …

G Vasiliev, I Chadaeva, D Rasskazov… - International Journal of …, 2021 - mdpi.com
Earlier, after our bioinformatic analysis of single-nucleotide polymorphisms of TATA-binding
protein-binding sites within gene promoters on the human Y chromosome, we suggested …

Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders

M Ponomarenko, E Sharypova, I Drachkova… - BMC Medical …, 2020 - Springer
Background Hemoglobin is a tetramer consisting of two α-chains and two β-chains of globin.
Hereditary aberrations in the synthesis of one of the globin chains are at the root of …

Group theory of syntactical freedom in DNA transcription and genome decoding

M Planat, MM Amaral, F Fang, D Chester… - Current Issues in …, 2022 - mdpi.com
Transcription factors (TFs) are proteins that recognize specific DNA fragments in order to
decode the genome and ensure its optimal functioning. TFs work at the local and global …

[HTML][HTML] An experimental study of the effects of SNPs in the TATA boxes of the GRIN1, ASCL3 and NOS1 genes on interactions with the TATA-binding protein

EB Sharypova, IA Drachkova, IV Chadaeva… - Vavilov Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract The GRIN1, ASCL3, and NOS1 genes are associated with various phenotypes of
neuropsychiatric disorders. For instance, these genes contribute to the development of …

In silico identification of variations in microRNAs with a potential impact on dairy traits using whole ruminant genome SNP datasets

C Bourdon, M Boussaha, P Bardou, MP Sanchez… - Scientific Reports, 2021 - nature.com
MicroRNAs are small noncoding RNAs that have important roles in the lactation process and
milk biosynthesis. Some polymorphisms have been studied in various livestock species from …

Genetics research at the" Centenary of human population genetics" conference and SBB-2019

TV Tatarinova, LE Tabikhanova, G Eslami, H Bai… - BMC genetics, 2020 - Springer
Maxat Zhabagin et al.[12](this issue) present population genetics study in continental Asia.
The authors analyzed the medieval Mongolian roots of paternal lineages from Kazakhstan …

Candidate SNP markers of atherogenesis significantly shifting the affinity of TATA-binding protein for human gene promoters show stabilizing natural selection as a …

M Ponomarenko, D Rasskazov, I Chadaeva… - International Journal of …, 2020 - mdpi.com
(1) Background: The World Health Organization (WHO) regards atherosclerosis-related
myocardial infarction and stroke as the main causes of death in humans. Susceptibility to …