Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in
critically ill patients. It is known to exert several important physiological and pharmacological …

Recently, the definition of sepsis was concluded to be a life-threatening organ dysfunction
caused by a dysregulated host response to infection. Severe patients always present with …

Background Several low-molecular-weight phenolic acids are present in the blood of septic
patients at high levels. The microbial origin of the most of phenolic acids in the human body …

The Mediterranean diet, rich in olive oil, is beneficial, reducing the risk of cardiovascular
diseases and cancer. Olive oil is mostly composed of the monounsaturated fatty acid omega …

Acute lung injury (ALI) and acute kidney injury (AKI) are major causes of sepsis-induced
mortality. The objective of the study is to evaluate the effect of tocilizumab (TCZ), an IL-6 …

The pathogenesis of sepsis and its progression to multiple organ dysfunction syndrome and
septic shock have been the subject of investigations for nearly half a century. Controversies …

Background Metrnl play an immunocytokine-like role in several diseases, which is also
known as meteorin-like because it is homologous to the neurotrophic factor meteorin …

BACKGROUND: Some of the postulated molecular mechanisms of sepsis progression are
linked with the imbalance between reactive oxygen species (ROS) production and its …

Sepsis is a systemic inflammatory response to infection and a major cause of morbidity and
mortality. Sildenafil (SLD) is a selective and potent inhibitor of cyclic guanosine …

Using a mitochondria-targeted vitamin E (Mito-Vit-E) in a rat pneumonia-related sepsis
model, we examined the role of mitochondrial reactive oxygen species in sepsis-mediated …