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Genetics of recurrent miscarriage: challenges, current knowledge, future directions
Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …
Mitochondria: participation to infertility as source of energy and cause of senescence
M Benkhalifa, YJ Ferreira, H Chahine, N Louanjli… - The international journal …, 2014 - Elsevier
Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …
[HTML][HTML] A systematic review of the impact of mitochondrial variations on male infertility
H Amor, ME Hammadeh - Genes, 2022 - mdpi.com
According to current estimates, infertility affects one in four couples trying to conceive.
Primary or secondary infertility can be due either to both partners or only to the man or the …
Primary or secondary infertility can be due either to both partners or only to the man or the …
Mitochondria in health and disease
Mitochondrial biology has become an area of intense research owing to the unique
physiology of the organelle and its role in several types of cancers and other disorders. It …
physiology of the organelle and its role in several types of cancers and other disorders. It …
Nuclear genome-encoded mitochondrial OXPHOS complex I genes in female buffalo show tissue-specific differences
EM Sadeesh, MS Lahamge, A Malik… - Molecular Biotechnology, 2024 - Springer
Buffalo physiology intricately balances energy, profoundly influencing health, productivity,
and reproduction. This study explores nuclear-mitochondrial crosstalk, revealing OXPHOS …
and reproduction. This study explores nuclear-mitochondrial crosstalk, revealing OXPHOS …
Impact of Mitochondrial Genetic Variants in ND1, ND2, ND5, and ND6 Genes on Sperm Motility and Intracytoplasmic Sperm Injection (ICSI) Outcomes
MA Al Smadi, ME Hammadeh, E Solomayer… - Reproductive …, 2021 - Springer
Sperm mitochondrial dysfunction causes the generation of an insufficient amount of energy
needed for sperm motility. This will affect sperm fertilization capacity, and thus, most …
needed for sperm motility. This will affect sperm fertilization capacity, and thus, most …
Mitochondrial DNA variations and mitochondrial dysfunction in Fanconi anemia
A Solanki, A Rajendran, S Mohan, R Raj, BR Vundinti - PLoS One, 2020 - journals.plos.org
In-vitro studies with different Fanconi anemia (FA) cell lines and FANC gene silenced cell
lines indicating involvement of mitochondria function in pathogenesis of FA have been …
lines indicating involvement of mitochondria function in pathogenesis of FA have been …
Mitochondrial dysfunction in pregnancy loss: a review
L Lu, X Huang, Y Shi, Y Jiang, Y Han… - Molecular and Cellular …, 2024 - Springer
A receptive endometrium, a healthy embryo, and harmonious communication between the
mother and the embryo/fetus are necessary for a healthy and successful pregnancy …
mother and the embryo/fetus are necessary for a healthy and successful pregnancy …
Mitochondrial DNA variations in ova and blastocyst: implications in assisted reproduction
Mitochondrial DNA (mtDNA) of oocyte is critical for its function, embryo quality and
development. Analysis of complete mtDNA of 49 oocytes and 18 blastocysts from 67 females …
development. Analysis of complete mtDNA of 49 oocytes and 18 blastocysts from 67 females …
Mitochondrial DNA variations are associated with recurrent pregnancy loss
A Azadi, DJ Seo, H Jafari Sasansara… - … DNA Part A, 2018 - Taylor & Francis
Cases with three or more consecutive spontaneous abortions before the 20th week of
gestation are termed as recurrent pregnancy loss (RPL). Problems in implantation of the …
gestation are termed as recurrent pregnancy loss (RPL). Problems in implantation of the …