Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as" resting versus activated" and" M1 versus M2." …

Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Microglia are mononuclear phagocytes of mesodermal origin that migrate to the central
nervous system (CNS) during the early stages of embryonic development. After colonizing …

As important immune cells, microglia undergo a series of alterations during aging that
increase the susceptibility to brain dysfunctions. However, the longitudinal characteristics of …

Brain macrophages include microglia in the parenchyma, border-associated macrophages
in the meningeal-choroid plexus-perivascular space, and monocyte-derived macrophages …

Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …

Microglia, the resident immune cells of the brain, have emerged as crucial regulators of
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …

Microglia are important immune cells in the central nervous system (CNS) that undergo
turnover throughout the lifespan. If microglial debris is not removed in a timely manner …

During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are
rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents …

Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …