Hypoxia-targeted drug delivery

A Sharma, JF Arambula, S Koo, R Kumar… - Chemical Society …, 2019 - pubs.rsc.org
Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …

Recent advances in emulsion-based delivery approaches for curcumin: From encapsulation to bioaccessibility

A Araiza-Calahorra, M Akhtar, A Sarkar - Trends in Food Science & …, 2018 - Elsevier
Background Curcumin has been widely acknowledged for its health-promoting effects.
However, its application is often limited by its poor water solubility and biochemical/structural …

Biopolymer poly-hydroxyalkanoates (PHA) production from apple industrial waste residues: A review

H Liu, V Kumar, L Jia, S Sarsaiya, D Kumar, A Juneja… - Chemosphere, 2021 - Elsevier
Apple pomace, the residue which is left out after processing of apple serves as a potential
carbon source for the production of biopolymer, PHA (poly-hydroxyalkanoates). It is rich in …

Curcumin delivery mediated by bio-based nanoparticles: a review

M Moballegh Nasery, B Abadi, D Poormoghadam… - Molecules, 2020 - mdpi.com
Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

Exosomes for the enhanced tissue bioavailability and efficacy of curcumin

F Aqil, R Munagala, J Jeyabalan, AK Agrawal… - The AAPS journal, 2017 - Springer
Exosomes are extracellular microvesicles with a particle size of 30–100 nm and carry a
cargo of proteins, lipids, RNA, and DNA. Their properties of shuttling in-and-out of the cells …

Therapeutic applications of curcumin nanoformulations

MM Yallapu, PKB Nagesh, M Jaggi, SC Chauhan - The AAPS journal, 2015 - Springer
Curcumin (diferuloylmethane) is a bioactive and major phenolic component of turmeric
derived from the rhizomes of curcuma longa linn. For centuries, curcumin has exhibited …

Bacterial polyhydroxyalkanoates-eco-friendly next generation plastic: production, biocompatibility, biodegradation, physical properties and applications

Muhammadi, Shabina, M Afzal… - Green Chemistry Letters …, 2015 - Taylor & Francis
Polyhydroxyalkanoates (PHAs) are intracellular aliphatic polyesters synthesized as energy
reserves, in the form of water-insoluble, nano-sized discrete and optically dense granules in …

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

S Wang, R Su, S Nie, M Sun, J Zhang, D Wu… - The Journal of nutritional …, 2014 - Elsevier
Nanotechnology is an innovative approach that has potential applications in nutraceutical
research. Phytochemicals have promising potential for maintaining and promoting health, as …

Curcumin can improve Parkinson's disease via activating BDNF/PI3k/Akt signaling pathways

T **, Y Zhang, BOA Botchway, J Zhang, R Fan… - Food and Chemical …, 2022 - Elsevier
Parkinson's disease is a common progressive neurodegenerative disease, and presently
has no curative agent. Curcumin, as one of the natural polyphenols, has great potential in …

Liposome-encapsulated curcumin-loaded 3D printed scaffold for bone tissue engineering

N Sarkar, S Bose - ACS applied materials & interfaces, 2019 - ACS Publications
Curcumin, the active constituent for turmeric, is known for its antioxidant, anti-inflammatory,
anticancer, and osteogenic activities. However, it shows extremely poor bioavailability, rapid …