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Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
[HTML][HTML] Mitochondrial dysfunction: pathophysiology and mitochondria-targeted drug delivery approaches
Mitochondria are implicated in a wide range of functions apart from ATP generation, and,
therefore, constitute one of the most important organelles of cell. Since healthy mitochondria …
therefore, constitute one of the most important organelles of cell. Since healthy mitochondria …
Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases
Y Zhang, H Yang, D Wei, X Zhang, J Wang, X Wu… - …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
[HTML][HTML] The impact of mitochondrial dysfunction in amyotrophic lateral sclerosis
J Zhao, X Wang, Z Huo, Y Chen, J Liu, Z Zhao, F Meng… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and highly fatal
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …
[HTML][HTML] The link between oxidative stress, redox status, bioenergetics and mitochondria in the pathophysiology of ALS
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease of the
motor system. It is characterized by the degeneration of both upper and lower motor …
motor system. It is characterized by the degeneration of both upper and lower motor …
The role of sonic hedgehog pathway in the development of the central nervous system and aging-related neurodegenerative diseases
C Yang, Y Qi, Z Sun - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The Sonic hedgehog (SHH) pathway affects neurogenesis and neural patterning during the
development of the central nervous system. Dysregulation of the SHH pathway in the brain …
development of the central nervous system. Dysregulation of the SHH pathway in the brain …
Emerging roles of dysregulated adenosine homeostasis in brain disorders with a specific focus on neurodegenerative diseases
CP Chang, KC Wu, CY Lin, Y Chern - Journal of Biomedical Science, 2021 - Springer
In modern societies, with an increase in the older population, age-related
neurodegenerative diseases have progressively become greater socioeconomic burdens …
neurodegenerative diseases have progressively become greater socioeconomic burdens …
[HTML][HTML] Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of …
Y Zhou, J Tang, J Lan, Y Zhang, H Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting
both upper and lower motor neurons (MNs) with large unmet medical needs. Multiple …
both upper and lower motor neurons (MNs) with large unmet medical needs. Multiple …
The role of Smo-Shh/Gli signaling activation in the prevention of neurological and ageing disorders
Sonic hedgehog (Shh) signaling is an essential central nervous system (CNS) pathway
involved during embryonic development and later life stages. Further, it regulates cell …
involved during embryonic development and later life stages. Further, it regulates cell …
New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by selective, early degeneration of motor neurons in the brain and spinal cord …
characterized by selective, early degeneration of motor neurons in the brain and spinal cord …