Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Mass spectrometry imaging under ambient conditions

C Wu, AL Dill, LS Eberlin, RG Cooks… - Mass spectrometry …, 2013 - Wiley Online Library
Mass spectrometry imaging (MSI) has emerged as an important tool in the last decade and it
is beginning to show potential to provide new information in many fields owing to its unique …

Mass spectrometry: recent advances in direct open air surface sampling/ionization

ME Monge, GA Harris, P Dwivedi… - Chemical …, 2013 - ACS Publications
This review discusses advances in the field of ambient sampling/ionization mass
spectrometry (“ambient MS” for short) with a focus on mechanistic and instrumentation …

Nano-DESI mass spectrometry imaging of proteoforms in biological tissues with high spatial resolution

M Yang, D Unsihuay, H Hu, F Nguele Meke… - Analytical …, 2023 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful tool for label-free map** of the spatial
distribution of proteins in biological tissues. We have previously demonstrated imaging of …

Spatial multiplexing and omics

JL Carstens, SN Krishnan, A Rao, AG Sorace… - Nature Reviews …, 2024 - nature.com
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …

Desorption electrospray ionization mass spectrometry: 20 years

NM Morato, RG Cooks - Accounts of chemical research, 2023 - ACS Publications
Conspectus Mass spectrometry (MS) is one of the most widely used technologies in the
chemical sciences. With applications spanning the monitoring of reaction products, the …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …