Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and has a
poor prognosis. Epigenetic modification has been shown to be deregulated during HCC …

Glioblastoma is characterized by widespread genetic and transcriptional heterogeneity, yet
little is known about the role of the epigenome in glioblastoma disease progression. Here …

Developmental tumors in children and young adults carry few genetic alterations, yet they
have diverse clinical presentation. Focusing on Ewing sarcoma, we sought to establish the …

Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

Parental effects influence offspring phenotypes through pre‐and post‐natal routes but little is
known about their molecular basis, and therefore their adaptive significance. Epigenetic …

Aberrant DNA methylation is a hallmark of cancer. However, our understanding of how
tumor cell-specific DNA methylation patterns are established and maintained is limited …

Even though the etiology of Alzheimer's disease (AD) remains unknown, it is suggested that
an interplay among genetic, epigenetic and environmental factors is involved. An increasing …

Salmon rickettsial septicaemia (SRS), caused by the bacteria Piscirickettsia salmonis (P.
salmonis), is responsible for significant mortality in farmed Atlantic salmon in Chile. Currently …

Cadmium exposure is ubiquitous and has been linked to diseases including cancers and
reproductive defects. Since cadmium is nonmutagenic, it is thought to exert its gene …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
the death of motor neurons, the aetiology of which is essentially unknown. Here, we present …