Cognitive ageing research examines the cognitive abilities that are preserved and/or those
that decline with advanced age. There is great individual variability in cognitive ageing …

Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

Abstract “The Scaffolding Theory of Aging and Cognition (STAC)”, proposed in 2009, is a
conceptual model of cognitive aging that integrated evidence from structural and functional …

What can be expected in normal aging, and where does normal aging stop and pathological
neurodegeneration begin? With the slow progression of age-related dementias such as …

For more than 50 years, psychologists, gerontologists, and, more recently, neuroscientists
have considered the possibility of successful aging. How to define successful aging remains …

The availability of neuroimaging technology has spurred a marked increase in the human
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …

Episodic memory and working memory decline with advancing age. Nevertheless, large-
scale population-based studies document well-preserved memory functioning in some older …

Abstract As coronavirus disease 2019 (COVID-19) and aging are both accompanied by
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …

Working memory, a fundamental cognitive function that is highly dependent on the integrity
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …

Age-related changes in brain structure result from a complex interplay among various
neurobiological processes, which may contribute to more complex trajectories than what can …