Nucleic acid-based cancer biomarkers (NABCBs) have emerged as a notable and
continuously captivating research focal point within the domain of oncology. As a result …

Triple-negative breast cancer (TNBC) is one of the most malignant tumors with poor
prognosis. Methuosis is a new type of nonapoptotic cell death characterized by the …

B cell lymphoma 6 (BCL6) is a conserved multi-domain protein that functions principally as a
transcriptional repressor. This protein regulates many pivotal aspects of immune cell …

Carnosic acid (CA), a phenolic tricyclic diterpene, has many biological effects, including anti-
inflammatory, anticancer, antiobesity, and antidiabetic activities. In this study, an efficient …

Conventional drug screening platforms face limitations such as single cell line analysis, slow
processing, unstable fluid flow, and frequent gradient adjustments, highlighting the …

Loss of function screens using shRNA (short hairpin RNA) and CRISPR (clustered regularly
interspaced short palindromic repeats) are routinely used to identify genes that modulate …

Therapy resistance remains a major challenge during the treatment of patients with
advanced cancer. Due to the complex nature of the cellular and molecular mechanisms …

X-box binding protein 1 (XBP1) is mainly expressed in breast cancer (BC) in human
cancers. Its tumorigenesis and favourable prognosis are contradictory, and its essential role …

High-grade serous ovarian cancer (HGSC) and colorectal carcinomas (CRC) are highly
aggressive malignancies accounting for a large number of cancer-related death worldwide …

Abstract B-cell lymphoma 6 (BCL6) is a transcriptional repressor essential for B lymphocyte
differentiation and germinal center formation through its BTB structural domain …