Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern
society. Underlying mechanisms show that stress is involved in the relationship between …

Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …

Central obesity is associated with insulin resistance and dyslipidemia. Thus, the
mechanisms that control fat distribution and its impact on systemic metabolism have …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

The recent dramatic rise in obesity rates is an alarming global health trend that consumes an
ever increasing portion of health care budgets in Western countries. The root cause of …

Obesity and dyslipidemia are risk factors for metabolic disorders including diabetes and
cardiovascular disease. Sphingolipids such as ceramide and glucosylceramides, while …

At pharmacological concentrations, glucocorticoids (GCs) display potent anti‐inflammatory
effects, and are therefore frequently prescribed by physicians to treat a wide variety of …

The present review provides evidence for the relationship between chronic stress,
alterations in HPA activity, and obesity. Understanding these associations and its …

Cushing's syndrome (CS) patients have increased mortality primarily due to cardiovascular
events induced by glucocorticoid (GC) excess-related severe metabolic changes. Glucose …