Hyperspectral imaging fluorescence excitation scanning for colon cancer detection

SJ Leavesley, M Walters, C Lopez… - … of biomedical optics, 2016 - spiedigitallibrary.org
Optical spectroscopy and hyperspectral imaging have shown the potential to discriminate
between cancerous and noncancerous tissue with high sensitivity and specificity. However …

Design of a tetra-band MIM plasmonic absorber based on triangular arrays in an ultra-compact MIM waveguide

SM Ebadi, S Khani - Optical and quantum electronics, 2023 - Springer
This paper presents design and numerical investigations of an ultra-compact, and highly-
efficient plasmonic absorber based on metal–insulator–metal waveguides. The proposed …

An approach for characterizing and comparing hyperspectral microscopy systems

NS Annamdevula, B Sweat, P Favreau, AS Lindsey… - Sensors, 2013 - mdpi.com
Hyperspectral imaging and analysis approaches offer accurate detection and quantification
of fluorescently-labeled proteins and cells in highly autofluorescent tissues. However …

Colorectal cancer detection by hyperspectral imaging using fluorescence excitation scanning

SJ Leavesley, J Deal, S Hill, WA Martin… - Optical Biopsy XVI …, 2018 - spiedigitallibrary.org
Hyperspectral imaging technologies have shown great promise for biomedical applications.
These techniques have been especially useful for detection of molecular events and …

A theoretical‐experimental methodology for assessing the sensitivity of biomedical spectral imaging platforms, assays, and analysis methods

SJ Leavesley, B Sweat, C Abbott… - Journal of …, 2018 - Wiley Online Library
Spectral imaging technologies have been used for many years by the remote sensing
community. More recently, these approaches have been applied to biomedical problems …

Hyperspectral multiphoton microscope for biomedical applications

AJ Bares, CB Schaffer, S Tilley - US Patent 10,394,008, 2019 - Google Patents
Optical sensing techniques and devices based on detection of fluorescent emissions at
different optical wavelengths by nonlinear optical absorption of different excitation beams at …

Multifaceted mirror array illuminator for fluorescence excitation-scanning spectral imaging microscopy

M Parker, SA Mayes, CM Browning… - Journal of …, 2023 - spiedigitallibrary.org
Significance Hyperspectral imaging (HSI) technologies offer great potential in fluorescence
microscopy for multiplexed imaging, autofluorescence removal, and analysis of …

Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry

H Choi, D Wadduwage, PT Matsudaira… - Biomedical optics …, 2014 - opg.optica.org
A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging
both in the spatial and the spectral domain. Images acquired through a standard imaging …

Automated image analysis of FRET signals for subcellular cAMP quantification

SJ Leavesley, A Nakhmani, Y Gao, TC Rich - cAMP Signaling: Methods …, 2015 - Springer
A variety of FRET probes have been developed to examine cAMP localization and dynamics
in single cells. These probes offer a readily accessible approach to measure localized cAMP …

Design of a modified endoscope illuminator for spectral imaging of colorectal tissues

CM Browning, S Mayes, TC Rich… - Optical Biopsy XV …, 2017 - spiedigitallibrary.org
The gold standard for locating colonic polyps is a white light endoscope in a colonoscopy,
however, polyps smaller than 5 mm can be easily missed. Modified procedures such as …