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The cholinergic system in the pathophysiology and treatment of Alzheimer's disease
Cholinergic synapses are ubiquitous in the human central nervous system. Their high
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
Review of pharmacotherapeutic targets in Alzheimer's disease and its management using traditional medicinal plants
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and impaired daily functioning. While there is currently no …
cognitive decline, memory loss, and impaired daily functioning. While there is currently no …
Gut microbiome alterations in Alzheimer's disease
NM Vogt, RL Kerby, KA Dill-McFarland, SJ Harding… - Scientific reports, 2017 - nature.com
Alzheimer's disease (AD) is the most common form of dementia. However, the
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …
Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier
DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
Effects of virtual reality intervention on cognition and motor function in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis
S Zhu, Y Sui, Y Shen, Y Zhu, N Ali, C Guo… - Frontiers in aging …, 2021 - frontiersin.org
Background: Virtual reality (VR) intervention is an innovative and efficient rehabilitative tool
for patients affected by stroke, Parkinson's disease, and other neurological disorders. This …
for patients affected by stroke, Parkinson's disease, and other neurological disorders. This …
[HTML][HTML] Acetylcholine bidirectionally regulates learning and memory
Q Huang, C Liao, F Ge, J Ao, T Liu - Journal of Neurorestoratology, 2022 - Elsevier
Acetylcholine (ACh) is one of the most important neurotransmitters in the central cholinergic
system; it specifically binds to muscarinic and nicotinic receptors and is degraded by …
system; it specifically binds to muscarinic and nicotinic receptors and is degraded by …
Current and future treatments for Alzheimer's disease
KG Yiannopoulou… - Therapeutic advances in …, 2013 - journals.sagepub.com
Alzheimer's dementia (AD) is increasingly being recognized as one of the most important
medical and social problems in older people in industrialized and non-industrialized …
medical and social problems in older people in industrialized and non-industrialized …
Neurodegenerative diseases: Regenerative mechanisms and novel therapeutic approaches
Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
New approaches for the treatment of Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent chronic neurodegenerative disease. Current
approved therapies are symptomatic treatments having some effect on cognitive function …
approved therapies are symptomatic treatments having some effect on cognitive function …